Objective To establish a method for the determination of residue of sulfur dioxide in traditional Chinese medicine. Methods The samples were extracted by wet distillation under acidic conditions,with 3% hydrogen peroxide as absorption liquid, and then determined by ion exchange- ion chromatography conductivity detection. The determination was performed on IonPac@ AS11- HC( 250 mm × 4 mm) ion exchange column with mobile phase consisted of 20 mmol / L KOH at a flow rate of 1 ml / min, the column temperature was set at 30 ℃,the detection cell temperature was set at 35 ℃. Results The linear range of sulphate was 1 ~ 200 μg / ml( r = 0. 999) with an average recovery of 80. 80% ~ 103. 07%( RSD = 1. 73% ~ 7. 62%). Conclusion The method is sensitive,specific,automatic and simple.

Objective: To investigate separation effect of iridoid glycosides from Cornus officinalis by different types of macroporous resin.Method: The content of loganin and morroniside from C.officinalis was determined by HPLC,effectiveness of different macroporous adsorption resin on separating iridoid glycosides from C.officinalis was investigated.Result: HPD-400 type of macroporous resin had the best separation effect.Regression equation of loganin and morroniside were Y = 17.245X + 13.362(r = 0.999 9),Y = 15.468X 41.275(r = 1.000 0);The linear range of them were 21.75-435,35.8-716 μg;Recoveries were 98.27%,96.29%,respectively.Conclusion: It was feasible that selected the content of loganin and morroniside as index to screen macroporous resin for enrichment iridoid glycosides from C.officinalis,this study could provide experimental basis for the follow-up study of separation of effective parts from C.officinalis.