Understanding the neural basis of social communication and vocal perception in primates is a key challenge in systems neuroscience. Vocalizations are fundamental for communication, and several cortical areas, known as "voice patches," have been identified as being sensitive to conspecific vocalizations in primates, vital for distinguishing species-specific calls. While the dorsal stream's role in complex auditory-motor functions and human speech processing is established, its specific contribution to processing species-specific vocalizations in non-human primates remains unclear. Using high-resolution fMRI (0.6 mm isotropic voxels), we investigated brain regions involved in processing vocalizations in awake rhesus monkeys exposed to coos, screams, and aggressive calls, among control sounds. Our analyses revealed a widespread network involved in vocalization processing, encompassing auditory-associated areas including the core and belt auditory cortices, as well as premotor, and somatosensory-related areas. Moreover, we found selective activation in the caudal part of the lateral sulcus (area Tpt) and the dorsal premotor cortex (area 6DR/F2) in response to vocalizations. Also, the population responses in these areas could discriminate between different vocalizations. Our results enhance our understanding of the neural basis of vocal communication in primates. Specifically, they highlight the involvement of a voice-related dorsal network in macaques, including Tpt and part of 6DR/F2, in processing the acoustic features of salient vocal stimuli, potentially linking them to motor representations. These findings provide insights into potential evolutionary precursors of auditory-motor pathways that support complex auditory communication systems in primates, including human speech.

Cryogenic tank chill and fill is an important cryogenic fluid management technology that supports and enables many of NASA's long-duration space missions. For no-vent fill, the receiver tank pressure remains below the supply tank pressure during the entire duration of the fill so that the tank does not require venting. This is especially advantageous for tank fill operations in low gravity where the position of the liquid is not always known and venting the tank may cause loss of propellant by venting liquid. In lieu of expensive tests conducted on-orbit, accurate computational models capable of predicting receiver tank pressure during cryogenic propellant tank fill may be used to reduce system and propellant mass as well as mission risk. However, these numerical models must be validated or anchored to test data. This study presents computational fluid dynamics (CFD) models with conjugate heat transfer that are used to predict a liquid hydrogen tank chill and no-vent fill ground test conducted at Lewis Research Center (now Glenn Research Center) in 1991. The specific test case chosen for model validation implemented an upward-facing jet near the bottom of a cylindrical 34 liter tank. CFD predictions are compared to experimental measurements of tank pressure, fill level, and wall temperature. The CFD results show reasonable agreement to the test data but overpredict the pressure collapse near the end of the fill despite the liquid jet penetrating the liquid-vapor interface.

Social communication draws on several cognitive functions such as perception, emotion recognition and attention. The association of audio-visual information is essential to the processing of species-specific communication signals. In this study, we use functional magnetic resonance imaging in order to identify the subcortical areas involved in the cross-modal association of visual and auditory information based on their common social meaning. We identified three subcortical regions involved in audio-visual processing of species-specific communicative signals: the dorsolateral amygdala, the claustrum and the pulvinar. These regions responded to visual, auditory congruent and audio-visual stimulations. However, none of them was significantly activated when the auditory stimuli were semantically incongruent with the visual context, thus showing an influence of visual context on auditory processing. For example, positive vocalization (coos) activated the three subcortical regions when presented in the context of positive facial expression (lipsmacks) but not when presented in the context of negative facial expression (aggressive faces). In addition, the medial pulvinar and the amygdala presented multisensory integration such that audiovisual stimuli resulted in activations that were significantly higher than those observed for the highest unimodal response. Last, the pulvinar responded in a task-dependent manner, along a specific spatial sensory gradient. We propose that the dorsolateral amygdala, the claustrum and the pulvinar belong to a multisensory network that modulates the perception of visual socioemotional information and vocalizations as a function of the relevance of the stimuli in the social context. SIGNIFICANCE STATEMENT: Understanding and correctly associating socioemotional information across sensory modalities, such that happy faces predict laughter and escape scenes predict screams, is essential when living in complex social groups. With the use of functional magnetic imaging in the awake macaque, we identify three subcortical structures-dorsolateral amygdala, claustrum and pulvinar-that only respond to auditory information that matches the ongoing visual socioemotional context, such as hearing positively valenced coo calls and seeing positively valenced mutual grooming monkeys. We additionally describe task-dependent activations in the pulvinar, organizing along a specific spatial sensory gradient, supporting its role as a network regulator.

Social interactions rely on the interpretation of semantic and emotional information, often from multiple sensory modalities. Nonhuman primates send and receive auditory and visual communicative signals. However, the neural mechanisms underlying the association of visual and auditory information based on their common social meaning are unknown. Using heart rate estimates and functional neuroimaging, we show that in the lateral and superior temporal sulcus of the macaque monkey, neural responses are enhanced in response to species-specific vocalisations paired with a matching visual context, or when vocalisations follow, in time, visual information, but inhibited when vocalisation are incongruent with the visual context. For example, responses to affiliative vocalisations are enhanced when paired with affiliative contexts but inhibited when paired with aggressive or escape contexts. Overall, we propose that the identified neural network represents social meaning irrespective of sensory modality.

ABSTRACT For educators to help children exposed to adverse life experiences, it is necessary to understand how adversity impacts different mechanisms of learning, emotion, and planning as these capacities underpin success in schools and beyond. The goal of this paper is to review essential findings on how early life adversity transforms the brain which, in turn, impacts educational outcomes. Part 1 begins by discussing the species‐specific and expectant experiences that guide typical development, and then turns to early life adversities and their relationship to both physical and mental health outcomes. Part 2 summarizes four dimensions of adversity— type , timing , term , and toxicity —and how each differentially impacts the developing brain, including individual differences in psychopathology. Part 3 discusses the relevance of these findings for educators, highlighting how behavior can be modified to build resilience and greater academic and social–emotional competency.

Social interactions rely on the interpretation of semantic and emotional information, often from multiple sensory modalities. In primates, both audition and vision serve the interpretation of communicative signals. Autistic individuals present deficits in both social communication and audio-visual integration. At present, the neural mechanisms subserving the interpretation of complex audio-visual social events are unknown. Based on heart rate estimates and functional neuroimaging, we show that macaque monkeys associate affiliative facial expressions or social scenes with corresponding affiliative vocalizations, aggressive expressions or scenes with corresponding aggressive vocalizations and escape visual scenes with scream vocalizations, while suppressing vocalizations that are incongruent with the visual context. This process is subserved by two distinct functional networks, homologous to the human emotional and attentional networks activated during the processing of visual social information. These networks are thus critical for the construction of social meaning representation, and provide grounds for the audio-visual deficits observed in autism. One-sentence summary Macaques extract social meaning from visual and auditory input recruiting face and voice patches and a broader emotional and attentional network.

Heart rate (HR) is extremely valuable in the study of complex behaviours and their physiological correlates in non-human primates. However, collecting this information is often challenging, involving either invasive implants or tedious behavioural training. In the present study, we implement a Eulerian video magnification (EVM) heart tracking method in the macaque monkey combined with wavelet transform. This is based on a measure of image to image fluctuations in skin reflectance due to changes in blood influx. We show a strong temporal coherence and amplitude match between EVM-based heart tracking and ground truth ECG, from both color (RGB) and infrared (IR) videos, in anesthetized macaques, to a level comparable to what can be achieved in humans. We further show that this method allows to identify consistent HR changes following the presentation of conspecific emotional voices or faces. EVM is used to extract HR in humans but has never been applied to non-human primates. Video photoplethysmography allows to extract awake macaques HR from RGB videos. In contrast, our method allows to extract awake macaques HR from both RGB and IR videos and is particularly resilient to the head motion that can be observed in awake behaving monkeys. Overall, we believe that this method can be generalized as a tool to track HR of the awake behaving monkey, for ethological, behavioural, neuroscience or welfare purposes.

Robotic Refueling Mission-3 (RRM3) is an external payload on the International Space Station (ISS) to demonstrate the techniques for storing and transferring a cryogenic fuel on orbit. RRM3 was designed and built at the National Aeronautics and Space Administration/Goddard Space Flight Center (NASA/GSFC). Initial testing was performed at GSFC using liquid nitrogen and liquid argon. Final testing and flight fill of methane was performed at the NASA Kennedy Space Center (KSC) to take advantage of KSC's facilities and expertise for handling a combustible cryogen. This paper gives an overview of the process and challenges of developing the payload and the results of its on-orbit performance.

Children often show signs of dysregulation, impulsivity, and risk-taking-behaviors that interfere with learning and growth. Commonly implicated in such interfering behaviors are problems of self-control. Several decades of research in the mind and brain sciences inform understanding of self-control, both as a trait and state. This research has significant implications for educators, providing strategies for assessing and strengthening self-control. This paper reviews the relevant theoretical concepts and practical applications. Part one discusses current thinking about the nature of self-control, focusing on the paired distinctions between (i) trait and state, as well as (ii) volitional and impulsive processes. Part two reviews a family of methods designed to assess different aspects of self-control. Part three focuses on ways to strength self-control, including simple strategies that help create habits and reduce conflict with competing temptations.

The mind and brain sciences have uncovered important details about the mechanisms underlying goal attainment, including strategies to overcome obstacles. A suite of self-regulatory strategies have made relatively little contact with education, despite cost-effective methods and striking results in both educational contexts as well as other areas that impinge, often negatively, on educational outcomes (e.g., nutrition, addictions). This review starts with a description of two of these strategies: (1) implementation intentions, in which a goal is framed as an IF-THEN statement where the IF defines the situational trigger or context and the THEN defines the behavioral response; (2) mental contrasting, in which an individual frames a goal as a contrast between a future wish and a current obstacle. Part 2 reviews the empirical literature as it pertains to education. Part 3 concludes with a discussion of future directions, including limitations and extensions to populations with mental health challenges.

In order to use oxygen that is produced on the surface of Mars from In-Situ production processes in a chemical propulsion system, the oxygen must first be converted from vapor phase to liquid phase and then stored within the propellant tanks of the propulsions system. There are multiple ways that this can be accomplished, from simply attaching a liquefaction system onto the propellant tanks to carrying separate tanks for liquefaction and storage of the propellant and loading just prior to launch (the way that traditional rocket launches occur on Earth). A study was done into these various methods by which the oxygen (and methane) could be liquefied and stored on the Martian surface. Five different architectures or cycles were considered: Tube-on-Tank (also known as Broad Area Cooling or Distributed Refrigeration), Tube-in-Tank (also known as Integrated Refrigeration and Storage), a modified Linde open liquefaction/refrigeration cycle, the direct mounting of a pulse tube cryocooler onto the tank, and an in-line liquefier at ambient pressure. Models of each architecture were developed to give insight into the performance and losses of each of the options. The results were then compared across eight categories: Mass, Power (both input and heat rejection), Operability, Cost, Manufacturability, Reliability, Volume-ility, and Scalability. The result was that Tube-on-Tank and Tube-in-Tank architectures were the most attractive solutions, with NASA's engineering management choosing to pursue tube on tank development rather than further differentiate the two. As a result NASA is focusing its Martian surface liquefaction activities and technology development on Tube-on-Tank liquefaction cycles.

Burkart et al.'s proposal is based on three false premises: (1) theories of the mind are either domain-specific/modular (DSM) or domain-general (DG); (2) DSM systems are considered inflexible, built by nature; and (3) animal minds are deemed as purely DSM. Clearing up these conceptual confusions is a necessary first step in understanding how general intelligence evolved.

Many have argued that the expressive power of human thought comes from language. Language plays this role, so the argument goes, because its generative computations construct hierarchically structured, abstract representations, covering virtually any content and communicated in linguistic expressions. However, language is not the only domain to implement generative computations and abstract representations, and linguistic communication is not the only medium of expression. Mathematics, morality, and music are three others. These similarities are not, we argue, accidental. Rather, we suggest they derive from a common computational system that we call the Universal Generative Faculty or UGF. UGF is, at its core, a suite of contentless generative procedures that interface with different domains of knowledge to create contentful expressions in thought and action. The representational signatures of different domains are organized and synthesized by UGF into a global system of thought. What was once considered the language of thought is, on our view, the more specific operation of UGF and its interfaces to different conceptual domains. This view of the mind changes the conversation about domain-specificity, evolution, and development. On domain-specificity, we suggest that if UGF provides the generative engine for different domains of human knowledge, then the specificity of a given domain (e.g., language, mathematics, music, morality) is restricted to its repository of primitive representations and to its interfaces with UGF. Evolutionarily, some generative computations are shared with other animals (e.g., combinatorics), both for recognition-learning and generation-production, whereas others are uniquely human (e.g., recursion); in some cases, the cross-species parallels may be restricted to recognition-learning, with no observable evidence of generation-production. Further, many of the differences observed between humans and other animals, as well as among nonhuman animals, are the result of differences in the interfaces: whereas humans promiscuously traverse (consciously and unconsciously) interface conditions so as to combine and analogize concepts across many domains, nonhuman animals are far more limited, often restricted to a specific domain as well as a specific sensory modality within the domain. Developmentally, the UGF perspective may help explain why the generative powers of different domains appear at different stages of development. In particular, because UGF must interface with domain-specific representations, which develop on different time scales, the generative power of some domains may mature more slowly (e.g., mathematics) than others (e.g., language). This explanation may also contribute to a deeper understanding of cross-cultural differences among human populations, especially cases where the generative power of a domain appears absent (e.g., cultures with only a few count words). This essay provides an introduction to these ideas, including a discussion of implications and applications for evolutionary biology, human cognitive development, cross-cultural variation, and artificial intelligence.

Gender, age, and culturally specific beliefs are often considered relevant to observed variation in social interactions. At present, however, the scientific literature is mixed with respect to the significance of these factors in guiding moral judgments. In this study, we explore the role of each of these factors in moral judgment by presenting the results of a web-based study of Eastern (i.e., Russia) and Western (i.e., USA, UK, Canada) subjects, male and female, and young and old. Participants (n = 659) responded to hypothetical moral scenarios describing situations where sacrificing one life resulted in saving five others. Though men and women from both types of cultures judged (1) harms caused by action as less permissible than harms caused by omission, (2) means-based harms as less permissible than side-effects, and (3) harms caused by contact as less permissible than by non-contact, men in both cultures delivered more utilitarian judgments (save the five, sacrifice one) than women. Moreover, men from Western cultures were more utilitarian than Russian men, with no differences observed for women. In both cultures, older participants delivered less utilitarian judgments than younger participants. These results suggest that certain core principles may mediate moral judgments across different societies, implying some degree of universality, while also allowing a limited range of variation due to sociocultural factors.

Moral agents are individuals who act in the moral sphere in such a way that they can be held morally responsible for their actions. Where different animals fit into the moral sphere may depend on their psychological properties. Objections to animals fitting somewhere in the moral sphere are typically based on their lack of some cognitive requirement, they aren't smart enough to have morality, or they only have simple emotions but lack the moral emotions. The issue then becomes the sort of capacity required to make the moral-looking behavior into truly moral behavior. As people learn more about animals, their lives free from human encroachment, their cognitive capacities, their emotions and their needs, the calibration method will be useful in order to help decide the place of animals in the moral sphere. The outcomes of such decisions depend greatly on the work of philosophers and psychologists who study moral …

The importance of game theoretic models to evolutionary theory has been in formulating elegant equations that specify the strategies to be played and the conditions to be satisfied for particular traits to evolve. These models, in conjunction with experimental tests of their predictions, have successfully described and explained the costs and benefits of varying strategies and the dynamics for establishing equilibria in a number of evolutionary scenarios, including especially cooperation, mating, and aggression. Over the past decade or so, game theory has been applied to model the evolution of language. In contrast to the aforementioned scenarios, however, we argue that these models are problematic due to conceptual confusions and empirical difficiences. In particular, these models conflate the comptutations and representations of our language faculty (mechanism) with its utility in communication (function); model languages as having different fitness functions for which there is no evidence; depend on assumptions for the starting state of the system, thereby begging the question of how these systems evolved; and to date, have generated no empirical studies at all. Game theoretic models of language evolution have therefore failed to advance how or why language evolved, or why it has the particular representations and computations that it does. We conclude with some brief suggestions for how this situation might be ameliorated, enabling this important theoretical tool to make substantive empirical contributions.

The ATLAS experiment is a general purpose detector aiming to fully exploit the discovery potential of the Large Hadron Collider (LHC) at CERN. It is foreseen that after several years of successful data-taking, the LHC physics programme will be extended in the so-called High-Luminosity LHC, where the instantaneous luminosity will be increased up to 5 × 1034 cm−2 s−1. For ATLAS, an upgrade scenario will imply the complete replacement of its internal tracker, as the existing detector will not provide the required performance due to the cumulated radiation damage and the increase in the detector occupancy. The current baseline layout for the new ATLAS tracker is an all-silicon-based detector, with pixel sensors in the inner layers and silicon micro-strip detectors at intermediate and outer radii. The super-module is an integration concept proposed for the strip region of the future ATLAS tracker, where double-sided stereo silicon micro-strip modules are assembled into a low-mass local support structure. An electrical super-module prototype for eight double-sided strip modules has been constructed. The aim is to exercise the multi-module readout chain and to investigate the noise performance of such a system. In this paper, the main components of the current super-module prototype are described and its electrical performance is presented in detail.