Previous articleNext article No AccessReviewsHelen Parish, Clerical Celibacy in the West: c. 1100–1700. (Catholic Christendom, 1300–1700). Farnham, Surrey, UK: Ashgate, 2010. Pp. xi, 282. $124.95. ISBN: 9780754639497.Megan McLaughlinMegan McLaughlin University of Illinois at Urbana-Champaign Search for more articles by this author University of Illinois at Urbana-Champaign PDFPDF PLUSFull Text Add to favoritesDownload CitationTrack CitationsPermissionsReprints Share onFacebookTwitterLinkedInRedditEmail SectionsMoreDetailsFiguresReferencesCited by Speculum Volume 88, Number 1January 2013 The journal of the Medieval Academy of America Article DOIhttps://doi.org/10.1017/S0038713413000420 Views: 25Total views on this site Copyright © The Medieval Academy of America 2013 PDF download Crossref reports no articles citing this article.

Patterns of episcopal power. Bishops in tenth and eleventh century western Europe. Edited by Ludger Körntgen and Dominik Wassenhoven. (Prinz-Albert-Forschungen, 6.) Pp. 226. Berlin–Boston: de Gruyter, 2011. €89.95 978 3 11 026202 5 - Volume 64 Issue 3

Journal Article Sari Katajala-Peltomaa. Gender, Miracles, and Daily Life: The Evidence of Fourteenth-Century Canonization Processes. (History of Daily Life, number 1.) Turnhout, Belgium: Brepols. 2009. Pp. 312. €70.00 Get access Sari Katajala-Peltomaa. Gender, Miracles, and Daily Life: The Evidence of Fourteenth-Century Canonization Processes. (History of Daily Life, number 1.) Turnhout, Belgium: Brepols. 2009. Pp. 312. €70.00. Megan McLaughlin Megan McLaughlin University of Illinois, Urbana-Champaign Search for other works by this author on: Oxford Academic Google Scholar The American Historical Review, Volume 116, Issue 2, April 2011, Pages 504–505, https://doi.org/10.1086/ahr.116.2.504 Published: 01 April 2011

That the sexual misconduct of a king had political ramifications is clear from a large number of texts from throughout the entire Middle Ages. At no point, however, was royal sexuality more salient in political writing than in the second half of the eleventh century. This was not simply a reflection of contemporary efforts to reform sexual morality. Neither can charges of sexual immorality be dismissed as mere rhetorical devices, intended to blacken a king's character (although they certainly did that). On the contrary, sex was doing important ideological work in political texts from this period. This article focuses on the particularly savage set of sexual accusations made against King (after 1084, Emperor) Henry IV of Germany (1056–1106). It argues that the long-standing association between sexual desire and privacy, shame and disorder worked powerfully in the eleventh century to justify rebellion, and to separate the king, as libidinous individual, from the ‘majesty’ of the office he held.

a bishop should revere and constantly review the lord's command: "let your loins be girded about, and your lights burning" [luke 12:35].He who wishes to carry burning lamps in his hands along with the wise virgins [Matthew 25:1-12], let him gird his loins.For if no one shall see God without chastity, how much more is this true for a bishop?For a bishop who is not chaste in mind and body, although he may appear to live, yet is dead and buried

This paper reports a formative analysis of a Math Modeling Tool in the Algebra II Cognitive Tutor. This tutor is designed to support algebraic reasoning about real world problems. This study focuses on reasoning about situations that can be modeled with general linear form expressions (c = ax + by). Formative evaluations of an early general linear form lesson showed that it helped students comprehend the underlying problem situations, but was less successful in helping students construct symbolic models of the situations. These evaluations guided design of a new tool to scaffold students’ understanding of the componential structure of these symbolic models and the mapping of model components to the problem situation. An empirical evaluation shows that the new tool successfully helps students understand the structure of these mathematical models and learn to construct them.

The ability of human complement regulatory molecules to prevent xenograft rejection following pig-to-primate xenotransplantation is limited. We assayed the efficacy of transgenic human decay accelerating factor (hDAF) expressed on porcine cells to inhibit the in vitro complement activity of primate sera. We measured the cytotoxic activity of baboon or human sera against peripheral blood lymphocytes (PBLs) from hDAF or nontransgenic pigs using a flow cytometry complement-mediated cytotoxicity assay (FCCA). We also analyzed the anti–Galα1-3Gal (αGal) antibody titer of the baboon sera by ELISA and the expression of hDAF and αGal on the PBL surface by immunofluorescence. Transgenic hDAF expression was capable of protecting pig cells against injury produced by both baboon and human serum. However, the hDAF molecule was more efficient against human than baboon sera. The humoral cytotoxicity capacity correlated with the level of both IgG and IgM anti-αGal antibodies. In addition, inhibition of complement-mediated cytotoxicity of hDAF pig cells correlated with the expression of hDAF and αGal molecules on target cells. These results confirm in vitro the protective role of hDAF in pig cells to heterologus complement mediated damage, but they also suggest that protection decreases in the presence of high levels of anti-porcine antibodies in serum, low expression of hDAF, or high expression of αGal on pig cells.

This paper examines the role of adaptive student modeling in cognitive tutor research and dissemination. Cognitive tutorsTM are problem solving environments constructed around cognitive models of the knowledge students are acquiring. Over the past decade we in the Pittsburgh Advanced Cognitive Tutor (PACT) Center at Carnegie Mellon have been employing a cognitive programming tutor in university-based teaching and research, while simultaneously developing cognitive mathematics tutors that are currently in use in about 150 schools in 14 states. This paper examines adaptive student modeling issues in these two contexts. We examine the role of student modeling in making the transition from the research lab to widespread classroom use, describe our university-based efforts to empirically validate student modeling in the ACT Programming Tutor, and conclude with a description of the key role that student modeling plays in formative evaluations of the Cognitive Algebra II Tutor.

BACKGROUNDTo prevent the central role played by complement activation in the hyperacute rejection of pig organs transplanted into primates, pigs transgenic for human decay-accelerating factor (HDAF) have recently been produced. The data presented here extend previous immunohistochemical findings by documenting the immunological characterization and the levels of expression of HDAF in these transgenic pigs.METHODSAnimals from 30 independently derived lines were included in this study. HDAF expression was characterized by immunoprecipitation and epitope mapping. Quantitative analysis was performed by radiometric assays followed by Scatchard analysis and by double-determinant radioimmunoassay. Deposition of iC3b on porcine aortic endothelial cells was determined by radioimmunoassay. DNA slot-blot analysis and densitometric scanning were used to evaluate HDAF transgene copy number.RESULTSThe integrity of HDAF expressed by these transgenic pigs could be demonstrated. HDAF was present in 72% of the organs analyzed, although considerable variation in expression occurred, both between animals and within the same pig. High levels of HDAF on porcine aortic endothelial cells resulted in iC3b deposition at levels as low as that detected on human endothelial cells. Twenty-six organs expressed levels of HDAF greater than those observed in the equivalent human tissue. HDAF expression did not correlate with the number of copies of the transgene incorporated into the porcine genome.CONCLUSIONSTransgenic pigs, which express levels of functional HDAF even greater than those observed in humans, have successfully been produced. Pigs transgenic for human complement inhibiting molecules could represent a source of organs for future clinical xenotransplantation.

Previous articleNext article No AccessReviews Auprès des Saints Corps et Âme: L'Inhumation "ad Sanctos" dans la Chrétienté d'Orient et d'Occident du IIIe au VIIe Siècle . Yvette DuvalMegan McLaughlinMegan McLaughlin Search for more articles by this author PDFPDF PLUS Add to favoritesDownload CitationTrack CitationsPermissionsReprints Share onFacebookTwitterLinkedInRedditEmail SectionsMoreDetailsFiguresReferencesCited by Speculum Volume 66, Number 2Apr., 1991 The journal of the Medieval Academy of America Article DOIhttps://doi.org/10.2307/2864164 Views: 1Total views on this site Copyright 1991 Medieval Academy of AmericaPDF download Crossref reports no articles citing this article.

Gender & HistoryVolume 3, Issue 2 p. 147-159 Gender Paradox and the Otherness of God MEGAN MCLAUGHLIN, MEGAN MCLAUGHLIN Associate Professor in the Department of History at the University of Illinois, Urbana-Champaign, U.S.A. She is working on a book entitled Sex, Gender and Power at the Time of the Investiture Controversy.Search for more papers by this author MEGAN MCLAUGHLIN, MEGAN MCLAUGHLIN Associate Professor in the Department of History at the University of Illinois, Urbana-Champaign, U.S.A. She is working on a book entitled Sex, Gender and Power at the Time of the Investiture Controversy.Search for more papers by this author First published: June 1991 https://doi.org/10.1111/j.1468-0424.1991.tb00121.xCitations: 4AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume3, Issue2June 1991Pages 147-159 RelatedInformation

(1990). The woman warrior: Gender, warfare and society in medieval Europe. Women's Studies: Vol. 17, No. 3-4, pp. 193-209.

Jerold Heiss. The Case of the Black Family: A Sociological Inquiry. New York & London: Columbia University Press, 1975. 246 pp. $13.50.