Background: To investigate the predictive value of preoperative peripheral blood inflammatory markers for surgical site infection (SSI) in laparoscopic radical gastrectomy for gastric cancer. Methods: A retrospective analysis was conducted on patients undergoing laparoscopic radical gastrectomy for gastric cancer, categorized into SSI and non-SSI groups based on postoperative SSI occurrences. Patient demographics, surgical details, laboratory results, and SSI incidence data were extracted. Differences in indicators, including neutrophil-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), and platelet-lymphocyte ratio (PLR), were assessed between the two groups. Multivariate logistic regression was utilized to determine the independent association of each indicator with SSI. Receiver operating characteristics (ROC) curve analysis was utilized to evaluate the predictive value of parameters. Results: Of 169 patients, 36 (21.30%) experienced SSI postoperatively. The SSI group exhibited higher preoperative NLR and SII (p < 0.05). After adjusting for variables, preoperative NLR (OR = 1.691, 95% CI: 1.211-2.417, p = 0.003) and SII (OR = 1.001, 95% CI: 1.000-1.002, p = 0.006) were identified as independent risk factors for SSI. Both NLR (AUC = 0.758, 95% CI: 0.666-0.850) and SII (AUC = 0.753, 95% CI: 0.660-0.850) demonstrated favorable diagnostic performance for predicting postoperative SSI. Conclusion: Preoperative NLR and SII significantly associate with postoperative SSI in laparoscopic radical gastrectomy for gastric cancer, making them valuable indicators for early prediction of SSI.

目的 了解重庆某三甲综合性医院医务人员发生血源性职业暴露的现况,分析危险因素、探讨预防措施.方法 采用回顾性调查,收集分析2019 年1 月1 日至2021 年12 月31 日血源性职业暴露事件.结果 在362 名血源性职业暴露事件中,以护理人员(37.85%,137/362)、学生(32.87%,119/362)为主;工作年限在 5 年及以下的医务人员(76.25%,276/362)多见;职业暴露方式以锐器伤为主(75.69%,274/362),手术(缝合/切开)是最常见的暴露环节;锐器伤的暴露部位以手部为主,皮肤及黏膜接触的暴露部位以眼部、手部为主.本次调查最常见的暴露源病原体为乙型肝炎病毒(HBV).结论 加强职业安全培训、遵守操作规范、加强医疗废物管理、接种乙肝疫苗等可降低暴露风险.

Objective To explore the risk factors,and control measures of cytomegalovirus（CMV）infection after hematopoietic stem cell transplantation（HSCT）in children with primary immunodeficiency diseases（PID）.Methods We retrospectively analyzed the results of 26 patients with PID-Wiskott-Aldrich syndrome（WAS,n=20）,severe combined immunodeficiency（SCID,n=1）,Xlinked chronic granulomatous disease（XCGD,n=2）and X-linked hyper-immunoglobulin M（Ig M）syndrome