Introduction: Ireland has the one of the lowest urologist per population ratios in Europe1 Out-patient department (OPD) visits are time consuming, costly and frequently patients cannot be reviewed in the intended timeframe2 With the COVID-19 crisis innovative virtual models of care are essential Methods: Patients for OPD review were assessed by a Consultant in a “virtual” clinic using electronic records (letters, imaging, blood results) and chart review if required Patients were either discharged, discharged for GP testing with specified re-referral criteria, phone/letter follow up by a LUTS clinical nurse specialist, investigated and reviewed by phone/letter, or returned for face-to-face consultation Results: 400 patients were assessed The majority were seen previously by SHO or junior registrar 160 (40%) patients were discharged directly via letter and advice 121 (30%) required further imaging and could be contacted by phone with the results 79 (20%) could be contacted by the LUTS clinical nurse specialist for phone/written review 40 (10%) necessitated face-to-face OPD review for clinical assessment or investigation review In 47 patients there was insufficient information available in the electronic platforms, thus requiring formal chart review Overall, 360 patients could be managed via “virtual” means The potential out-patient cost savings were estimated at €27,000 Conclusion: With this COVID-19 pandemic, innovative models of care are necessitated Introduction of a “virtual” OPD clinic allows reliable review of patients with reduced face-to-face follow-up attendances Further study of staff training and patient satisfaction is required

42 Impact of COVID-19 on a one-stop haematuria

32 Fabrication of artificial kidney stones of different physical properties for ex vivo

Introduction: The rising cost of healthcare requires rethinking in terms of resource utilisation care delivery. Nurse-led PSA phone follow-up clinics may provide a suitable option. Materials and methods: 815 patients were recruited for the nurse-led stable prostate cancer telephone follow-up service. A convenience sample was selected for postal questionnaire assessment of their satisfaction. Results: 815 patients had 3683 phone-call follow ups over 10 years. Patients’ own understanding of condition varied from average (76.3%) and good (9.2%) in the majority. 87.2% found the service convenient and 75.6% informative. 95.3% found the telephone assessment preferable to attending the outpatient department. 87.2% were keen on savings on transport/travel. 53.5% found it more reassuring. 91.9% of patients felt that everything they wanted to talk about was covered. Discussion: This service can be delivered in a high volume nurse-led service, with high levels of patient satisfaction, as an innovative service development.

Oesophageal adenocarcinoma is an exemplar model of obesity-associated cancer. Locally advanced disease is treated with neoadjuvant chemoradiotherapy, and survival rates are highest in patients demonstrating a pathological response following neoadjuvant therapy. Given that 55 % of oesophageal adenocarcinoma patients are obese, uncovering the effect of adipose tissue on radioresponse is clinically relevant. This study investigates if adipose tissue activates genomic instability events in radioresponsive (OE33P) and radioresistant (OE33R) oesophageal cancer cell lines and tumour samples.