The research adopted the chicken breast meat as the main raw material adding yeast,sugar,etc.The formula of the fried fermentation chicken string was studied by single factor and orthogonal experiment methods.The single factor experiment mainly includes fermentation time impact on the quality of products(and make sure that the fermentation eventually pH value impact on the quality of products),best kefir and establishing sugar dosage of impact on the quality of products.But because they can effect each other,so the interaction between orthogonal experiment through further determine the optimal combination.Orthogonal experiments prove the best combination for fermentation time 11 h,sugar dosage 4.5%,kefir dosage 7%.