One case of endometrioid undifferentiated carcinoma with choriocacinomatous differentiation was observed clinically and pathologically with HE staining and immunohistochemistry.The results showed that,the endometrial neoplasia was about 3.0 cm×2.5 cm.The low-differentiated tumor cells were arranged in solid nets with scant stroma,marked atypically,multinucleated syncytial cells and convoluted nuclei.The tumor cells stained positively for CK7(+),syncytial cells negatively for ER(-),PR(-),CD68(-) positively for HCG(+).Endometrioid undifferentiated carcinoma with choriocacinomatous differentiation is a rare entity with features of higher malignant tumor,and the prognosis is difficult to be evaluated for rare cases reported.

目的 探讨无功能性甲状旁腺癌的临床病理特征.方法 对1例无功能性甲状旁腺癌进行临床病理特点分析和免疫组化标记,选用的抗体为上皮膜抗原(EMA)、细胞角蛋白(CK)、甲状腺球蛋白(TG)、甲状腺转录因子-1(TTF-1)、甲状旁腺激素(PTH),并进行相关文献复习.结果 患者为老年女性,肿物位于右侧甲状腺近被膜处,呈灰白色实性,组织学见癌细胞呈梁状,胞浆较丰富,部分区域胞浆透明,免疫组化显示EMA(+)、CK部分(+)、TG(-)、TTF-1(-)、PTH(+).结论 无功能性甲状旁腺癌是一种罕见恶性肿瘤,其诊断和鉴别诊断主要依据组织形态学和免疫组织化学特征.