基本信息
浏览量:0
职业迁徙
个人简介
The long-term goals of my laboratory are to increase understanding of the life cycles of mucosal pathogens, to develop ways to treat or prevent infections by them, and to help train the next generation of biomedical researchers and teachers. We use Vibrio cholerae as a model pathogen in our research. V. cholerae is a motile, waterborne bacterium that maintains a substantial environmental reservoir, and causes endemic and epidemic cholera in many parts of the world.
Our primary research focus is identifying V. cholerae genes and their protein products that are expressed during the infection process and during transmission, and then elucidating their regulation and function. We have chosen this focus because bacteria generally express genes only when and where needed and thus do not readily reveal their pathogenic armament outside of the infected host. Detailed knowledge of the behavior of pathogens and the antigens they express during infection and transmission are crucial to development of more effective vaccines, antimicrobials and diagnostics. In the course of our studies, we have created a number of genetic tools, some of which are now used widely in the research community.
Our primary research focus is identifying V. cholerae genes and their protein products that are expressed during the infection process and during transmission, and then elucidating their regulation and function. We have chosen this focus because bacteria generally express genes only when and where needed and thus do not readily reveal their pathogenic armament outside of the infected host. Detailed knowledge of the behavior of pathogens and the antigens they express during infection and transmission are crucial to development of more effective vaccines, antimicrobials and diagnostics. In the course of our studies, we have created a number of genetic tools, some of which are now used widely in the research community.
研究兴趣
论文共 210 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Nick Lee,Manmeet Bhalla, Joana M. Pereira,Stacie Clark,Sara E. Roggensack, Alenka Lovy, Michael J. Pereira, Guillermo Arroyo,Walter Adams,Andrew Camilli,Rodney K. Tweten,John M. Leong,
biorxiv(2024)
Gut pathogensno. 1 (2023): 17-14
Jacob Bourgeois,Andrew Camilli
Cold Spring Harbor protocolsno. 10 (2023): pdb.top107867-pdb.top107867
Cold Spring Harbor protocols (2023)
Jacob Bourgeois,Andrew Camilli
Cold Spring Harbor protocolsno. 10 (2023): 108185-108185
Advances in experimental medicine and biology (2023): 149-173
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn