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RESEARCH INTERESTS
Dr Mowday's main research involves the use of the tumour-selective, non-pathogenic, anaerobic bacterium Clostridium sporogenes in the context of cancer therapy. As part of an international multidisciplinary collaboration, she is using C. sporogenes to deliver imageable prodrug-activating genes selectively to tumours (Clostridium-directed Enzyme Prodrug Therapy, CDEPT). She is also investigating the use of C. sporogenes as an immune adjuvant to improve the effectiveness of cancer immunotherapies.
Additional research interests include non-invasive imaging techniques (bioluminescence, microCT, microPET) and the development of orthotopic tumour models for more clinically relevant testing of novel therapeutics.
研究兴趣
论文共 36 篇作者统计合作学者相似作者
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Alexandra M. Mowday, Jella M. van de Laak, Zhe Fu, Kimiora L. Henare,Ludwig Dubois,Philippe Lambin,Jan Theys,Adam V. Patterson
Aleksandra M Kubiak, Jella van de Laak,Yanchao Zhang, Tom S Bailey,Luuk Claessen,Philip Hittmeyer, Carlijn Vlaswinkel,Alexsandra Mowday,Ludwig J Dubois,Jan Theys
Future microbiologyno. 7 (2023): 385-388
ACS MEDICINAL CHEMISTRY LETTERSno. 11 (2023): 1517-1523
Amir Ashoorzadeh,Alexandra M Mowday,Christopher P Guise,Shevan Silva,Matthew R Bull,Maria R Abbattista,Janine N Copp,Elsie M Williams,David F Ackerley, Adam V Patterson, Jeff B Smaill
Alexandra M. Mowday,Ludwig J. Dubois,Aleksandra M. Kubiak,Jasmine V. E. Chan-Hyams,Christopher P. Guise,Amir Ashoorzadeh,Philippe Lambin,David F. Ackerley, Jeff B. Smaill,Nigel P. Minton,Jan Theys, Adam V. Patterson
Maria R Abbattista,Amir Ashoorzadeh,Christopher P Guise,Alexandra M Mowday, Rituparna Mittra,Shevan Silva, Kevin O Hicks,Matthew R Bull,Victoria Jackson-Patel,Xiaojing Lin,Gareth A Prosser,Neil K Lambie,
Dean C. Singleton,Alexandra M. Mowday,Chris P. Guise,Sophie P. Syddall,Sally Y. Bai,Dan Li,Amir Ashoorzadeh, Jeff B. Smaill,William R. Wilson, Adam V. Patterson
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