基本信息
views: 6
Career Trajectory
Bio
The Baird research laboratory integrates a broad range of experimental approaches to investigate molecular mechanisms of receptor-mediated cell signaling that enables cells to sense and respond to environmental cues. Much of our work has focused on the high affinity receptor (FcεRI) for immunoglobulin E (IgE), which sensitizes mast cells to antigen and thereby plays a pivotal role in initiating inflammatory and allergic immune responses. We employ quantitative microscopy and other biophysical methods to monitor changes in the distributions and dynamics of receptors and signaling components that accompany cellular response activities, which we measure in parallel. A particular area of interest is the role of cellular membranes in regulating and targeting signaling pathways. We have long worked to characterize IgE-FcεRI- mediated signaling in RBL mast cells as a model system for addressing fundamental questions of cellular response mechanisms initiated by other receptors and environmental factors. Similarly, we are translating the experimental techniques and cell response concepts developed in our work to elucidate mechanisms in other cell types, including those involved in cancer and neurodegenerative diseases.
Research Interests
Papers共 361 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Biophysical journalno. 15 (2023): 2256-2270
Jacob A. Erstling,Nirmalya Bag,Thomas C. Gardinier,Ferdinand F. E. Kohle,Naedum Domnwachukwu,Scott D. Butler,Teresa Kao,Kai Ma,Melik Z. Turker,Grant B. Feuer,Rachel Lee,Nada Naguib, James F. Tallman,Henry F. Malarkey,Lieihn Tsaur, William L. Moore,Dana V. Chapman,Tangi Aubert,Saurabh Mehta,Richard A. Cerione,Robert S. Weiss,Barbara A. Baird,Ulrich B. Wiesner
Advanced materialsno. 1 (2023)
bioRxiv the preprint server for biology (2023)
Multiphoton Microscopy in the Biomedical Sciences XXII (2022)
Load More
Author Statistics
#Papers: 361
#Citation: 13919
H-Index: 65
G-Index: 113
Sociability: 7
Diversity: 0
Activity: 1
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn