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职业迁徙
个人简介
Application of structural biology tools for the structure-function studies of relevant biological macromolecules, which include RNA polymerases, neurophysins and their hormone complexes, glutathione transferases, glutamine binding protein and complex, aldehyde dehydrogenase, augmenter of liver regeneration, green fluorescent protein, hemerythrin, myohemerythrin, ferrochelatase and plant cell wall polysaccharides. Application of multidisciplinary methodologies for structural genomics and structural proteomics. Development of advanced instrumentation for diffraction studies including synchrotron X-ray sources, remote access for beamline operations, robotic sample mounting technologies, and in-house X-ray sources. Development of computer software packages for Direct Crystallography - phasing from unlabelled native crystals, signal-based data collection, cost-effective high-throughput structure determination pipelines, and refinement methods to ensure high-quality structural results.
Research Areas:
Medicinal Chemistry & Chemical Biology
Structural Biology
研究兴趣
论文共 253 篇作者统计合作学者相似作者
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Acta Crystallographicano. a1 (2023): A287-A287
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John Rose,Dayong Zhou,Zheng-Qing Albert Fu,Zhongmin Jin,John Gonczy,John Chrzas,Palani Kandavelu, Rodrick Salazar, Maaz Gul,Lirong Chen,Bi-Cheng Wang,Unmesh Chinte
Acta Crystallographica Section A Foundations and Advancesno. a1 (2019)
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