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个人简介
Chris Goodnow’s research explores how the body’s immune system learns to fight off infections without damaging its own tissues. A pioneering exponent of mouse molecular genetics, Chris has found new ways to reveal how an animal’s genes interact with exposure to its environment to produce unique characteristics.
Having uncovered the sequence of checkpoints that prevent immune cells from producing antibodies to ‘self’ tissues, he has opened the way to new treatments for autoimmune diseases such as lupus and type 1 diabetes. In his latest research, Chris is using high-throughput DNA sequencing to look for connections between autoimmune disease and cancers of the immune system known as lymphoma.
Chris’s links with industry include founding a new biotechnology company to develop his mouse molecular genetics platform. He is the recipient of numerous awards, including the GSK Award for Research Excellence, and was elected a member of the US National Academy of Sciences in 2013.
研究兴趣
论文共 456 篇作者统计合作学者相似作者
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biorxiv(2024)
Erika Della Mina,Katherine J. L. Jackson, Alexander J. I. Crawford,Megan L. Faulks, Karrnan Pathmanandavel, Nicolino Acquarola, Michael O’Sullivan,Tessa Kerre,Leslie Naesens, Karlien Claes,Christopher C. Goodnow,Filomeen Haerynck,
Katrina L. Randall, Inge E. A. Flesch,Yan Mei,Lisa A. Miosge,Racheal Aye,Zhijia Yu, Heather Domaschenz,Natasha A. Hollett,Tiffany A. Russell, Tijana Stefanovic,Yik Chun Wong,Sandali Seneviratne,
Antoine Guérin,Marcela Moncada-Vélez,Katherine Jackson,Masato Ogishi,Jérémie Rosain,Mathieu Mancini,David Langlais, Andrea Nunez, Samantha Webster,Jesse Goyette,Taushif Khan,Nico Marr,
The Journal of experimental medicineno. 5 (2024)
Grant J Logan,Mario Mietzsch,Neeta Khandekar,Arlene D'Silva, Daniel Anderson,Mawj Mandwie,Jane Hsi, Austin R Nelson,Paul Chipman,Jennifer Jackson,Peter Schofield,Daniel Christ,
Molecular therapy : the journal of the American Society of Gene Therapyno. 7 (2023): 1979-1993
biorxiv(2023)
Tom Le Voyer, Audrey V. Parent,Xian Liu, Axel Cederholm, Adrian Gervais,Jeremie Rosain, Tina Nguyen, Malena Perez Lorenzo,Elze Rackaityte, Darawan Rinchai,Peng Zhang, Lucy Bizien,
Frontiers in Immunology (2023): 1095257-1095257
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