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Dorret I. Boomsma (born 18 November 1957, Huizen, The Netherlands) is a Dutch biological psychologist specializing in genetics and twin studies.
After receiving her Ph.D., Boomsma received an appointment as an assistant professor at the Vrije Universiteit in the Department of Psychonomics. In 1994 she became associate and in 1998 full professor and head of the Department of Biological Psychology。
Boomsma has built a database of over 75,000 twins and family members in The Netherlands, which has been used for dozens of twin studies. The twins and their families have undergone periodic testing over a period of decades, providing a mass of longitudinal data for statistical analysis. A large number of participants have also provided DNA, blood, and urine samples for testing. Her research has primarily focused on better understanding the influence of heredity on various physical and mental diseases, including cardiovascular diseases, pediatric bipolar disorder, and depression. This work has been reported in over 450 published papers and one book and has led to many awards for Boomsma.
Twin studies provide a way to understand how genotype affects an observable characteristic (called a phenotype). In short, identical (monozygotic) twins carry the same alleles for 100% of their genes whereas fraternal (dizygotic) twins will carry different alleles at 50% of the genes for which their parents had different genotypes. So if some characteristic (say, depression) that is observed in one identical twin is always observed in the other one, but this does not hold for fraternal twins, then one can conclude that heredity plays an important role in causing the condition.
Boomsma has been a pioneer in collecting a broad spectrum of data (e.g., medical histories, IQ tests, MRI scans) and biological material (e.g., DNA and RNA samples, blood and urine samples) from thousands of twins and analyzing them to determine the role of genetics in characteristics as varied as adult height, brain volume, intelligence, migraine headaches, anxiety, drug addiction, and love of coffee.
Her results span a wide range of behavioral characteristics, including discovery of the surprisingly large genetic component to feelings of loneliness, the fact that first borns have higher IQs than their younger siblings, and the increased influence of genetics on body weight as children grow older.
研究兴趣
论文共 292 篇作者统计合作学者相似作者
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Bodine M.A. Gonggrijp, Steve G.A. van de Weijer, Catrien C.J.H. Bijleveld,Dorret I Boomsma,Jenny van Dongen
biorxiv(2024)
Ella Davyson,Xueyi Shen,Floris Huider,Mark Adams, Karen Borges,Daniel McCartney, Lauren Barker,Jenny Van Dongen,Dorret Boomsma,Antoine Weihs,Hans Grabe, Luise Kuehn,
crossref(2024)
Nature Mental Healthpp.1-12, (2024)
Anna Gui,Anja Hollowell,Emilie M. Wigdor, Morgan J. Morgan,Laurie J. Hannigan,Elizabeth C. Corfield,Veronika Odintsova,Jouke-Jan Hottenga,Andrew Wong,René Pool, Harriet Cullen,Siân Wilson,
crossref(2024)
Jeffrey J Beck, John L Slunecka,Brandon N Johnson, Austin J Van Asselt,Casey T Finnicum,Cheryl Ageton,Amy Krie, Heidi Nickles,Kenneth Cowan,Jessica Maxwell,Dorret I Boomsma,Eco de Geus,
medrxiv(2024)
Nikki Hubers,Fiona A. A. Hagenbeek,Rene Pool,Sebastien Dejean,Amy C. C. Harms,Peter J. J. Roetman, Catharina E. M. van Beijsterveldt,Vassilios Fanos,Erik A. A. Ehli,Robert R. J. M. Vermeiren,Meike Bartels,Jouke Jan Hottenga,
HUMAN REPRODUCTIONno. 1 (2024): 35-42
Camiel M. Van der Laan,Hill F. Ip,Marijn Schipper,Jouke-Jan Hottenga,Eva M. L. Krapohl,Isabell Brikell,María Soler Artigas, Judith Cabana-Domínguez,Llonga Natalia,Ilja M. Nolte,Beate St Pourcain,Koen Bolhuis,
crossref(2024)
GENESno. 7 (2023): 1497-1497
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