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A cell biologist, Klionsky is renowned for his pioneering contributions to the understanding of autophagy, the process by which cells break down to survive stress conditions such as starvation, and the role autophagy plays in cancer, neurodegenerative diseases and other areas of human health.
Working with baker’s yeast cells, Klionsky characterized the protein pathways and signaling mechanisms by which a cell senses and responds to its environment. He also identified the cytoplasm-to-vacuole targeting pathway, a type of selective autophagy. His lab was the first to demonstrate endoplasmic reticulum stress-induced autophagy and autophagy in zebrafish.
Working with baker’s yeast cells, Klionsky characterized the protein pathways and signaling mechanisms by which a cell senses and responds to its environment. He also identified the cytoplasm-to-vacuole targeting pathway, a type of selective autophagy. His lab was the first to demonstrate endoplasmic reticulum stress-induced autophagy and autophagy in zebrafish.
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AUTOPHAGYno. 1 (2024): 1-3
Nature Cell Biologyno. 3 (2024): 307-308
CANCER LETTERS (2024): 216659-216659
Shree Padma Metur,Daniel J. Klionsky
FEBS LETTERSno. 1 (2024): 32-47
Xin Chen,Andrey S. Tsvetkov,Han-Ming Shen,Ciro Isidoro, Nicholas T. Ktistakis,Andreas Linkermann,Werner J. H. Koopman,Hans-Uwe Simon,Lorenzo Galluzzi, Shouqing Luo,Daqian Xu,Wei Gu,
AUTOPHAGYpp.1-34, (2024)
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