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职业迁徙
个人简介
Principal Research Interests
Comparative and evolutionary genomics: comparison of prokaryotic and eukaryotic genomes with the aim of predicting gene functions, constructing evolutionary scenarios for particular gene families and functional categories, and deciphering general evolutionary trends. An evolutionary phenomenon we are particularly interested in is horizontal gene transfer between diverse organisms. One of the important outcomes of research in this area is the system of Clusters of Orthologous Genes (COGs).
Discovery of new viruses in metagenomes and metatranscriptomes.
Evolution of the virosphere and hierarchical taxonomy of viruses.
Virus-host coevolution and evolution of antivirus defense systems in prokaryotes and eukaryotes.
Microevolution of pathogenic viruses, in particular, during epidemics, including COVID-19.
Evolutionary regimes of human cancers,
Exploitation of genome comparisons, particularly, those between relatively close genomes, for addressing fundamental issues of evolutionary biology such as the nature and intensity of adaptation and selection in different categories of genes and different organismal lineages.
General physical principles of evolution; origin and evolution of complexity; evolution as learning; thermodynamics of evolution.
Comparative and evolutionary genomics: comparison of prokaryotic and eukaryotic genomes with the aim of predicting gene functions, constructing evolutionary scenarios for particular gene families and functional categories, and deciphering general evolutionary trends. An evolutionary phenomenon we are particularly interested in is horizontal gene transfer between diverse organisms. One of the important outcomes of research in this area is the system of Clusters of Orthologous Genes (COGs).
Discovery of new viruses in metagenomes and metatranscriptomes.
Evolution of the virosphere and hierarchical taxonomy of viruses.
Virus-host coevolution and evolution of antivirus defense systems in prokaryotes and eukaryotes.
Microevolution of pathogenic viruses, in particular, during epidemics, including COVID-19.
Evolutionary regimes of human cancers,
Exploitation of genome comparisons, particularly, those between relatively close genomes, for addressing fundamental issues of evolutionary biology such as the nature and intensity of adaptation and selection in different categories of genes and different organismal lineages.
General physical principles of evolution; origin and evolution of complexity; evolution as learning; thermodynamics of evolution.
研究兴趣
论文共 1296 篇作者统计合作学者相似作者
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Kira S. Makarova, Victor Tobiasson, Yuri I. Wolf,Zhongyi Lu, Yang Liu,Siyu Zhang, Mart Krupovic, Meng Li,Eugene V. Koonin
bioRxiv : the preprint server for biology (2024)
bioRxiv : the preprint server for biology (2024)
ISME COMMUNICATIONSno. 1 (2024): ycad011-ycad011
bioRxiv : the preprint server for biology (2024)
ISME JOURNALno. 1 (2024)
Physical Review Researchno. 2 (2024)
Syun-ichi Urayama,Akihito Fukudome,Miho Hirai,Tomoyo Okumura, Yosuke Nishimura,Yoshihiro Takaki,Norio Kurosawa,Eugene V. Koonin,Mart Krupovic, Takuro Nunoura
Nature Microbiologyno. 2 (2024): 514-523
Shan Zhao,Kira S. Makarova, Wenchao Zheng, Le Zhan, Qianqian Wan,Yafei Liu,Han Gong, Mart Krupovic,Joe Lutkenhaus,Xiangdong Chen,Eugene V. Koonin,Shishen Du
Nature Microbiologyno. 3 (2024): 712-726
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