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The central goal of research in the Balskus group is to discover, understand, and manipulate microbial metabolism. The vast majority of life on Earth is microbial, and the survival of these organisms in diverse habitats and complex communities requires chemical innovation. Understanding microbial metabolism at the molecular level is essential, as the metabolic functions of these organisms shape the environment, influence human health, and provide us with medicinally and industrially useful molecules.
The Balskus lab is uncovering new metabolic pathways and enzymes in microbial genome sequencing data, focusing on enzymes that perform interesting and novel chemistry, and elucidating the biochemical functions of genes linked to important biological activities with a particular emphasis on functions of the human microbiome. They are also devising strategies for integrating synthetic organic chemistry with microbial metabolism by developing biocompatible, non-enzymatic chemical transformations capable of modifying cellular metabolites. All of the group’s research integrates knowledge of microbiology with an understanding of biochemical logic and organic chemistry.
The Balskus lab is uncovering new metabolic pathways and enzymes in microbial genome sequencing data, focusing on enzymes that perform interesting and novel chemistry, and elucidating the biochemical functions of genes linked to important biological activities with a particular emphasis on functions of the human microbiome. They are also devising strategies for integrating synthetic organic chemistry with microbial metabolism by developing biocompatible, non-enzymatic chemical transformations capable of modifying cellular metabolites. All of the group’s research integrates knowledge of microbiology with an understanding of biochemical logic and organic chemistry.
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论文共 214 篇作者统计合作学者相似作者
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Nature Chemistryno. 2 (2024): 173-182
Bin Bao, Youyuan Wang, Pavl Boudreau,Xinyang Song,Meng Wu,Xi Chen,Izabel Patik,Ying Tang,Jodie Ouahed, Amit Ringel, Jared Barends,Chuan Wu,
Cellular and molecular gastroenterology and hepatology (2024)
Chenhao Li, Martin Stražar, Ahmed M.T. Mohamed, Julian A. Pacheco, Rebecca L. Walker, Tina Lebar, Shijie Zhao, Julia Lockart, Andrea Dame, Kumar Thurimella, Sarah Jeanfavre, Eric M. Brown,
Cellno. 8 (2024): 1834-1852.e19
bioRxiv : the preprint server for biology (2024)
Bin Bao, Youyuan Wang, Pavl Boudreau, Xinyang Song,Meng Wu,Xi Chen,Izabel Patik,Ying Tang,Jodie Ouahed,Chuan Wu,Emily Balskus,Jay Thiagarajah,
INFLAMMATORY BOWEL DISEASESno. 3 (2024): S63-S63
Amanda Mandarino Alves, Chiara Lecchi,Sharon Lopez,Alessia Stornetta,Prince Mathai,Peter Villalta,Emily Balskus,Silvia Balbo,Alexander Khoruts
Gastroenterologyno. 5 (2024): S-1168-S-1169
crossref(2024)
Paula Pelayo,Fatima A Hussain,Caroline A Werlang,Chloe Wu,Benjamin M Woolston,Katharina Ribbeck, Doug S Kwon,Emily P Balskus
biorxiv(2024)
Maria Altshuller, Xu He, Elliot J MacKrell,Kevin M Wernke, Joel W H Wong, Selene Sellés-Baiget,Ting-Yu Wang,Tsui-Fen Chou,Julien P Duxin,Emily P Balskus,Seth B Herzon,Daniel R Semlow
bioRxiv : the preprint server for biology (2024)
Amelia Y. M. Woo,Miguel Aguilar A. Ramos,Rohan Narayan, Khyle C. Richards-Corke,Michelle L. Wang,Walter J. Sandoval-Espinola,Emily P. Balskus
NATURE REVIEWS CHEMISTRYno. 7 (2023): 525-525
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