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I'm interested in the interplay between theory and experiment in natural science. New measurement technologies like single-cell RNA sequencing are bringing ‘big data’ to biology. My group develops mathematical tools for analyzing time-courses of high-dimensional gene expression data, leveraging tools from optimal transport, at the intersection of probability, statistics, and optimization. With the theory we develop, we aim to answer questions like: How does a stem cell transform into a muscle cell, a skin cell, or a neuron? How can we reprogram a skin cell into a neuron?
I'm interested in the interplay between theory and experiment in natural science. New measurement technologies like single-cell RNA sequencing are bringing ‘big data’ to biology. My group develops mathematical tools for analyzing time-courses of high-dimensional gene expression data, leveraging tools from optimal transport, at the intersection of probability, statistics, and optimization. With the theory we develop, we aim to answer questions like: How does a stem cell transform into a muscle cell, a skin cell, or a neuron? How can we reprogram a skin cell into a neuron?
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论文共 34 篇作者统计合作学者相似作者
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Abdull J. Massri,Alejandro Berrio,Anton Afanassiev,Laura Greenstreet, Krista Pipho,Maria Byrne,Geoffrey Schiebinger, David R. McClay,Gregory A. Wray
biorxiv(2024)
Yu-Chen Cheng,Yun Zhang,Shubham Tripathi, BV Harshavardhan,Mohit Kumar Jolly,Geoffrey Schiebinger,Herbert Levine,Thomas O. McDonald,Franziska Michor
biorxiv(2024)
ANNALS OF APPLIED PROBABILITYno. 1A (2024): 428-500
Becca Bonham-Carter,Geoffrey Schiebinger
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Cell systemsno. 10 (2023): 844-859.e4
Nature Communicationsno. 1 (2023): 1-15
CoRR (2023)
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arXiv (Cornell University) (2023)
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Yale S. Michaels,Matthew C. Major, Becca Bonham-Carter, Jingqi Zhang,Tiam Heydari,John M. Edgar,Laura Greenstreet,Roser Vilarrasa-Blasi, Seungjoon Kim,Elizabeth L. Castle,Aden Forrow, M Iliana Ibanez-Rios,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
arXiv (Cornell University) (2023)
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