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个人简介
My research focuses on the genetics and genomics of complex genetic disorders, especially alcohol and other substance use disorders. It spans interrelated areas that extend from genome-wide searches for genes affecting the risk for disease to molecular studies of the mechanisms by which associated variants affect gene expression, and from studies of the regulation of individual genes to genome-wide studies of expression using RNAseq and ATAC-seq, and includes the development of high throughput assays to identify functional elements in the genome. My research bridges human, animal and cellular studies to approach these complex disorders from multiple angles. I am one of the founders and leaders of the Substance Use Disorders working group of the Psychiatric Genomics Consortium, which is assembling meta-analyses to find genes affecting risk for alcohol and other substance disorders, and of the Collaborative Study on the Genetics of Alcoholism, which is a family-based study combining GWAS and functional studies to help understand the disorder.
研究兴趣
论文共 837 篇作者统计合作学者相似作者
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The American journal of psychiatryno. 4 (2024): 269-271
Xindi Li, Jiayi Liu,Andrew Boreland, Sneha Kapadia, Siwei Zhang, Alessandro Stillitano, Yara Abbo, Lorraine Clark,Dongbing Lai, Yunlong Li,Peter Barr,Jacquelyn Meyers,
biorxiv(2024)
Research square (2024)
medRxiv : the preprint server for health sciences (2024)
Nature geneticspp.1-17, (2024)
bioRxiv : the preprint server for biology (2024)
Behavior Geneticsno. 2 (2024): 151-168
bioRxiv : the preprint server for biology (2024)
ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCHno. 2 (2024): 283-294
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