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职业迁徙
个人简介
I was promoted as full professor in 2008 and working for Medical College of Soochow University, Suzhou, China. I established Soochow University Key Laboratory of Cancer Molecular Genetics in 2009, and visited University of Alabama at Birmingham (UAB) as a visiting professor in 2011. We are interested in the association between TGF-beta/Smad signaling and non-small cell lung cancer (NSCLC). My current research are mainly focusing on four aspects: 1.DNA methylation of Decorin 5'-UTR is associated with enhanced TGF-beta/Smad signaling in high-metastatic NSCLC cells. 2. JAK/STAT3 signaling is essential for TGF-beta-induced epithelial-mesenchymal transition (EMT) in NSCLC cells. 3. MicroRNA-based mechanism underlying reduced expression of TGFBR1 in NSCLC. 4. Non-coding RNA (miRNA, lncRNA and circRNA)-related mechanistic roles in TGF-beta-induced EMT and metastasis of NSCLC cells.
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论文共 51 篇作者统计合作学者相似作者
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International Orthopaedicspp.1-9, (2024)
International orthopaedicsno. 8 (2023): 1995-2001
Journal of visualized experiments : JoVE (2022)
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