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个人简介
Dr. Sahel is known worldwide for his expertise in vision restoration techniques. He has developed several interventions— including stem cell implantation, gene therapy, innovative pharmacologic approaches, and retinal prostheses—for retinitis pigmentosa, other retinal dystrophies, age-related macular degeneration, and other vision impairments that currently are untreatable e.g. Leber Hereditary Optic Neuropathy. Over the past decade he has led pioneering efforts in optogenetic vision restoration, a technique in which cells in the retina are genetically modified to express light sensitive proteins. This therapeutic technique has the potential to help patients who are blind or visually impaired as a result of a genetic defect. His team has developed novel high resolution imaging technologies for retinal and optic nerve conditions. Dr. Sahel also brings a strong neuroscience perspective to ophthalmology research, such as exploring the application of brain-computer interface technology.
Dr. Sahel is a co-inventor on more than 40 patents, several of which have led to start-up companies including Fovea Pharmaceuticals which Dr. Sahel founded and later was acquired by Sanofi Aventis. He also is a scientific co-founder of GenSight Biologics Inc., Pixium Vision Inc., Tilak Healthcare, Chronolife, Prophesee, Sparing Vision,.. He is a member of 11 editorial boards, including the Journal of Clinical Investigation and Science Translational Medicine.
Dr. Sahel is a co-inventor on more than 40 patents, several of which have led to start-up companies including Fovea Pharmaceuticals which Dr. Sahel founded and later was acquired by Sanofi Aventis. He also is a scientific co-founder of GenSight Biologics Inc., Pixium Vision Inc., Tilak Healthcare, Chronolife, Prophesee, Sparing Vision,.. He is a member of 11 editorial boards, including the Journal of Clinical Investigation and Science Translational Medicine.
研究兴趣
论文共 1443 篇作者统计合作学者相似作者
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Bingjie Wang,RAZIEH GANJEE, IRONA KHANDAKER, KEEVON FLOHR, YUANHANG HE,GUANG LI,JOSHUA WESALO,JOSÉ-ALAIN SAHEL, SUSANA DA SILVA,Shaohua Pi
Biomedical Optics Express (2024)
Valerie Fontaine, Thinhinane Boumedine,Elodie Monteiro,Mylene Fournie, Gendre Gersende,Jose-Alain Sahel,Serge Picaud,Stanislas Veillet,Rene Lafont,Mathilde Latil,Pierre J. Dilda,Serge Camelo
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 5 (2024): 3037
Sonny Caplash,Manuel Paez-Escamilla,Mark Westcott,Kunal K. Dansingani, Chad Indermill, Nacima Kisma, Eric Frau,Jose-Alain Sahel,Bahram Bodaghi,Vishal Jhanji,Marie-Helene Errera
Cold Spring Harbor Perspectives in Medicine (2024)
Journal of inherited metabolic disease (2024)
Alessio Antropoli,Lorenzo Bianco,Christel Condroyer,Aline Antonio, Julien Navarro, Dorothée Dagostinoz, Amine Benadji,José-Alain Sahel, Christina Zeitz,Isabelle Audo
Ophthalmology (2024)
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