基本信息
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职业迁徙
个人简介
Current Research
Dr. Kopp leads a translational research group within the Kidney Disease Section, Kidney Diseases Branch, studying focal segmental glomerulosclerosis (FSGS) and related podocyte diseases.
Recent Highlights
Chromosome 22 harbors a major risk locus for kidney disease in African Americans, including FSGS, HIV-associated nephropathy, and arterionephrosclerosis (hypertension-attributed kidney disease). APOL1 coding variants, which protect against trypanosomal infection, are strongly associated with kidney disease (odds ratios 7-29). The mechanism of glomerular injury is unknown.
The HIV-1 protein Vpr, expressed in the glomerular podocytes, is sufficient to reproduce the chief features of HIV-associated collapsing glomerulopathy in transgenic mice.
研究兴趣
论文共 519 篇作者统计合作学者相似作者
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biorxiv(2024)
Khamis Mustafa, Ying Han,Dan He,Ying Wang, Nan Niu,Pedro A. Jose,Yinong Jiang,Jeffrey B. Kopp,Hewang Lee,Peng Qu
PLOS ONEno. 2 (2024)
Journal of the American Society of Nephrology : JASN (2024)
Murli U Purswani,Denise L Jacobson,Linda A DiMeglio,Tzy-Jyun Yao,Jeffrey B Kopp,Russell B Van Dyke, Wendy Yu,George K Siberry, Pediatric AIDS/Cohort Study (PHACS)
Laboratory investigation; a journal of technical methods and pathologyno. 5 (2024): 100336-100336
Stanley Lipkowitz,Kei Kudo,Daniel Crooks, Yoshimi Greer, Ye Yang,Jeffrey Brender,Teruhiko Yoshida,Brittney Harrington,Rahul Kamdar,Soumya Korrapati,Yusuke Shibuya, Leah Henegar,
crossref(2024)
HLAno. 4 (2023): 377-378
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Journal of translational medicineno. 1 (2023): 1-19
2023 IEEE Western New York Image and Signal Processing Workshop (WNYISPW)pp.1-5, (2023)
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