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个人简介
His current research interest is respiratory infection and aging in airways. During aging, pulmonary function progressively deteriorates and pulmonary inflammation increases, accompanied by structural changes, and also it causes higher risk of infection (virus, bacteria and fungi) and amplified infection-induced inflammation. Novel agents including senolytic and senostatic agents might provide new therapeutic approaches to the respiratory infection in vulnerable population. Furthermore, he has a strong track record in inhaled drug discovery and is keen to develop novel inhaled agents against antimicrobial resistant bacteria, fungus and virus, for lung cancer or refractory progressive airway remodelling.
研究兴趣
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EUROPEAN RESPIRATORY JOURNAL (2023)
EUROPEAN RESPIRATORY JOURNAL (2023)
Hugo C. J. Ombredane,Peter S. Fenwick,Peter J. Barnes,Mona Bafadhel,Kazuhiro Ito,Louise E. Donnelly,Jonathan R. Baker
American journal of respiratory cell and molecular biologyno. 3 (2023): 339-341
Jonathan Baker, Hugo Ombredane,Leah Daly,Ian Knowles,Garth Rapeport,Kazuhiro Ito, Miguel Angel Martinez
ANTIMICROBIAL AGENTS AND CHEMOTHERAPYno. 1 (2023): e0105023-e0105023
Yuki Nishimoto, Daiki Ando, Kosuke Irie, Ikumi Kainuma,Yuki Katayama,Shiori Sato,Tomohiro Suzuki, Mai Harada,Tsubasa Yoshida,Kazuhiro Ito,Yasuo Kizawa
Molecular pharmaceuticsno. 4 (2023): 1933-1941
EUROPEAN RESPIRATORY JOURNAL (2023)
Frontiers in medicine (2023): 1144050
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