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We study molecular mechanisms underlying muscle specializations and patho-physiology of muscle diseases. Topics include developmental changes of muscle as a whole that lead to the formation of unique skeletal muscle group such as the extraocular muscle (EOM), control of muscle size by growth / developmental factors, as well as formation of synapses or neuromuscular junctions). This research is also interesting from a disease perspective since some of these molecules / pathways (e.g. myostatin, utrophin) offer therapeutic strategies for muscular dystrophy.
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Shiyang Song,Yefei Wen, Hui Tong,Emanuele Loro,Yingyun Gong,Jidong Liu, Sungguan Hong,Lei Li,Tejvir S Khurana,Maoping Chu,Zheng Sun
Journal of molecular cell biologyno. 2 (2019): 133-143
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