Mark Peakman
教授
Peter Gorer Department of Immunobiology
School of Immunology & Microbial Sciences, Faculty of Life Sciences & Medicine, King’s College London;Department of Diabetes, School of Cardiovascular Medicine & Sciences, Faculty of Life Sciences & Medicine, King’s College London
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个人简介
He subsequently returned to the UK and now oversees a research group at King’s College London in the Department of Immunobiology. The main focus of the research is the role of T lymphocytes in the aetiology of the autoimmune disease, Type 1 diabetes. In particular, the group has defined the critical targets for T cells that appear to have a role in the destruction of insulin-producing cells, and key immunological pathways through which this damage is mediated. More recently, the work has led to the definition of targets enabling the design of a novel approach to therapy. This strategy, termed “peptide immunotherapy” is the first of its kind in diabetes and further phases of this programme are ongoing. In the future, a better understanding of the role of the immune response in Type 1 diabetes will promote the further development of these novel therapeutics into the clinical setting. In addition, Mark has taken a role in designing and implementing mechanistic studies in the context of clinical trials of novel immunotherapies in type 1 diabetes.
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论文共 290 篇作者统计合作学者相似作者
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Diabetologiano. 11 (2023): 1983-1996
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EBioMedicine (2023): 104740-104740
Latif Rachdi,Zhicheng Zhou,Claire Berthault, Chloe Lourenço, Alexis Fouque, Thomas Domet,Mathieu Armanet,Sylvaine You,Mark Peakman,Roberto Mallone,Raphael Scharfmann
eBioMedicine (2023): 104740
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eBioMedicine (2023): 104625-104625
Jose Juan Almagro Armenteros,Caroline Brorsson, Christian Holm Johansen,Karina Banasik,Gianluca Mazzoni,Robert Moulder,Karoliina Hirvonen,Tomi Suomi,Omid Rasool,Sylvaine FA Bruggraber,M Loredana Marcovecchio, Emile Hendricks,
medRxiv (Cold Spring Harbor Laboratory) (2023)
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