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个人简介
Dr. Munendra Singh Tomar is currently a Research Associate at the Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Anschutz Medical Campus, in Prof. Dai’s laboratory, where he has been since 2021. His work focused on understanding the CAR T cells and engineered T cell therapies for autoimmune diseases such as Type 1 diabetes (T1D) and Rheumatoid Arthritis (RA). He had been working on T cell-mediated metal hypersensitivities, Redox signaling, and drug designing in immune diseases and infectious diseases to define the molecular mechanisms of T cell activation by metal ions. Furthermore, to characterize the transcriptomic and metabolic impacts of metal ions on T cells. Specifically, he has been understanding the role of neoantigens formed through post-translational modifications (PTMs) at the peptides that create the pathogenic neoepitopes and may drive autoimmune disease.
Before this, he worked on understanding the potential clinical usefulness of aspirin and other non-steroid anti-inflammatory drugs (NSAID) naproxen for prostate cancer prevention and deciphering the cancer immune biomarkers employing preclinical mice models in the same department since 2019 with Prof. Agarwal.
Prior to his Postdoctoral experience in the USA, he had a brief postdoctoral experience at the Indian Institute of Technology (IIT), BHU at Varanasi, Uttar Pradesh, India, with Prof. Pradip Paik. Here he studied the synthesizing nanocapsules from the Need seeds and formulating them for targeted delivery specifically for metastatic breast cancer. His post-doctoral work related to Need seed-based nanocapsule used for cancer therapy has been field an Indian patent. Dr. Tomar is a trained Cancer Immunologist who received his Ph.D. in 2017 from the Department of Zoology, Banaras Hindu University, Varanasi, India. He worked with Prof. Acharya on understanding the molecular mechanism and regulation of NK cell functions by CD4+CD25+ FoxP3+ regulatory T cells in a tumor-bearing host. Dr. Tomar has authored several research papers published in peer-reviewed journals and a few of his papers are under communications. He also serves as a reviewer for ACS Applied Bio-Materials and Frontiers in Physiology Journals.
研究兴趣
论文共 26 篇作者统计合作学者相似作者
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BIOMEDICAL MATERIALSno. 2 (2024)
Robin Kumar,Akhilendra K. Maurya, Lakshmi S. Bugata,Md. I. Kabir,Munendra Tomar,Rajesh Agarwal,Elizabeth P. Ryan,Komal Raina
CANCER RESEARCHno. 7 (2023): 4229-4229
Materials advancesno. 20 (2023): 4718-4731
Research Square (Research Square) (2023)
Cancer Immunology, Immunotherapyno. 6 (2022): 1429-1444
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作者统计
#Papers: 26
#Citation: 309
H-Index: 10
G-Index: 17
Sociability: 4
Diversity: 3
Activity: 4
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