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We aim to characterise fundamental mechanisms controlling lymphocyte development and function. In the future, explaining how these are integrated will be an important step towards a systems level understanding of immunity. Genetically modified mice in which the functions of signalling pathways and RNA–binding proteins (RBP) can be controlled by conditional mutagenesis are one important research tool. We also use genome wide approaches to study RNA turnover and translation and to identify the targets of RBP. Our approach trains individuals who can combine molecular, cellular and in vivo skills with the ability to generate and interpret big data and apply these to tackle important biological questions.
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论文共 346 篇作者统计合作学者相似作者
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Nordin D. Zandhuis,Aurelie Guislain, Abeera Popalzij, Sander Engels,Branka Popovic,Martin Turner,Monika C Wolkers
biorxiv(2024)
Hannah L. Sunshine,Andrew C. Cicchetto,Karolina Elzbieta Kaczor-Urbanowicz,Feiyang Ma, Danielle Pi, Chloe Symons,Martin Turner,Vipul Shukla,Heather R. Christofk,Thomas A. Vallim,M. Luisa Iruela-Arispe
CELL REPORTSno. 1 (2024): 113627-113627
LIFE SCIENCE ALLIANCEno. 2 (2024)
EUROPEAN JOURNAL OF IMMUNOLOGYno. 2 (2024): e2350700-e2350700
Louise S. Matheson,Georg Petkau, Beatriz Sáenz-Narciso,Vanessa D’Angeli, Jessica McHugh,Rebecca Newman,Haydn Munford,James West,Krishnendu Chakraborty,Jennie Roberts,Sebastian Łukasiak,Manuel D. Díaz-Muñoz,
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