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Using the immune system as a cancer treatment has the potential to induce long-term, durable remissions, and perhaps even cures for some patients. The T cells of the immune system are able to specifically kill the target cells they recognize. T cells are also able to persist in the body for many years, and form immune ‘memory,’ which enables the possibility of long-term protection. The Maus laboratory is interested in using genetic engineering techniques to re-direct T cells to find and kill tumor cells while sparing healthy tissues. We aim to: develop new ways to design molecular receptors to target T cells to liquid and solid tumors; use T cells as delivery vehicles for other drugs, and use drugs to help T cells work against tumors; and understand how T cells can work as “living drugs” to treat patients with cancer.
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论文共 327 篇作者统计合作学者相似作者
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Blood advancesno. 4 (2024): 1053-1061
Trends in cancerno. 4 (2024): 312-331
Marc Wehrli,Samantha Guinn,Filippo Birocchi, Adam Kuo,Yi Sun,Rebecca C Larson, Antonio J Almazan,Irene Scarfò,Amanda A Bouffard,Stefanie R Bailey, Praju Vikas Anekal, Paula Montero Lopis,
Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Magdi Elsallab,Moataz Ellithi, Matthew A. Lunning, Christopher D’Angelo,Jihyun Ma,Miguel-Angel Perales,Matthew Frigault,Marcela V. Maus
Blood (2024)
Korneel Grauwet,Trisha Berger,Michael C Kann, Harrison Silva,Rebecca Larson,Mark B Leick,Stefanie R Bailey,Amanda A Bouffard, David Millar, Kathleen Gallagher,Cameron J Turtle, Matthew J Frigault,
Journal for immunotherapy of cancerno. 5 (2024)
Michael C. Kann, Emily M. Schneider, Antonio J. Almazan, Isabel C. Lane,Amanda A. Bouffard,Valentina M. Supper, Hana N. Takei,Alexander Tepper,Mark B. Leick,Rebecca C. Larson,Benjamin L. Ebert,Marcela V. Maus,
Leukemiano. 3 (2024): 590-600
Matthew J Frigault, Charlotte E Graham,Trisha R Berger,Julie K. Ritchey,Nora Horick,Areej El-Jawahri,Irene Scarfò,Andrea Schmidts, Nicholas Haradhvala,Marc Wehrli, Won-Ho Lee, Aiyana Parker,
Blood Journal (2024)
Nature Medicineno. 2 (2024): 338-341
Nicholas J. Haradhvala,Marcela V. Maus
BLOOD CANCER DISCOVERYno. 2 (2024): 86-89
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