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Research in the Cell Biology Section spans the basic sciences, clinical trials, and epidemiology. Bench work involves methods of cell and molecular biology, immunology, and virology. Blood cell production in healthy individuals and especially in patients with bone marrow failure is the main theme. Advanced techniques most recently include single cell RNAseq, CRISPR-Cas9 gene editing, multicolored bar coded flow cytometry, and SomaLogic deep proteomics. Use of patient samples is encouraged, as the Hematology Branch clinic for patients with aplastic anemia, paroxysmal nocturnal hemoglobinuria (PNH), myelodysplastic syndromes (MDS), large granular lymphocytosis (LGL), and constitutional marrow failure is one of the largest in the world. Results in the laboratory have had real impact on the care of patients with these life-threatening illnesses, and access to patient samples over time and with therapeutic perturbation makes the laboratory strategies both innovative and concrete.
研究兴趣
论文共 994 篇作者统计合作学者相似作者
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Saravanan Ganesan, Rebecca M. Murray,Jesus Sotelo, Elliot O. Eton, Kouhei Takashima, Theo Botella, Kai Beattie, Alyssa C. Indart, Nada Chraiki, Carolyne Croizier, Franco Izzo,Catherine Potenski,
biorxiv(2024)
Zehra Tombul,Waled Bahaj, Merve Ozturk,Bhavisha Patel, Ahmet Toprak,Ibrahim Ibrahim,Weina Chen,Franklin Fuda,Olisaemeka D. Ogbue,Carmelo Gurnari,Charles Parker,Neal S. Young,
BRITISH JOURNAL OF HAEMATOLOGY (2024)
Zehra Tombul,Waled Bahaj, Merve Ozturk,Bhavisha Patel, Ahmet Toprak,Ibrahim Ibrahim,Weina Chen,Franklin Fuda,Olisaemeka D Ogbue,Carmelo Gurnari,Charles Parker,Neal S Young,
British journal of haematology (2024)
Fernanda Gutierrez-Rodrigues,Kristina Wells,Adrianna Jones, Dalton Hironaka, Cameron Rankin,Massimo Gadina, Keith A. Sikora,Lemlem Alemu,Rodrigo T. Calado,Kaitlin A. Quinn,Bhavisha Patel,Neal S. Young,
ANNALS OF THE RHEUMATIC DISEASESno. 4 (2024): 508-517
Cristina A Tentori, Lin P Zhao, Benedetta Tinterri, Kathryn E Strange, Katharina Zoldan,Konstantinos Dimopoulos,Xingmin Feng,Elena Riva, Benjamin Lim,Yannick Simoni, Vidhya Murthy,Madeline J Hayes,
HemaSphereno. 5 (2024): e64-e64
Ashvind Prabahran,Jibran Durrani, Juan Coelho Da Silva,Ruba Shalhoub,Jennifer Lotter,Olga Rios,Colin O. Wu,Bhavisha Patel,Neal Young,Emma M. Groarke
HemaSphereno. S3 (2023): e8904593-e8904593
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Robert Peter Gale, Wolfgang Hinterberger,Neal S. Young,Andrew R. Gennery,Christopher C. Dvorak,Kyle M. Hebert,Michael Heim,Larisa Broglie,Mary Eapen
Leukemiano. 6 (2023): 1191-1193
Bhavisha A. Patel,Marcela Ferrada,Kaitlin Quinn, Kristy Freeman,Ivana Darden,Wendy Goodspeed, Lisa Duncan, Roxanne Merkel,Alice Fike,Peter C Grayson,Neal S. Young,Emma M. Groarke
Blood (2023): 703
LFB Catto,EM Groarke,DV Clé,BA Santana,AP Azambuja,MM Oliveira, R Shalhoub, C Bomfim,NS Young, F Gutierrez-Rodrigues,R Calado
Hematology, Transfusion and Cell Therapy (2023): S11-S12
Roma V. Rajput, Dalton Hironaka,Ruba Shalhoub,Lemlem Alemu,Emma M. Groarke,Jennifer Lotter,Olga Rios,Ivana Darden,Colin O. Wu,Fernanda Gutierrez-Rodrigues,Xingmin Feng,Neal S. Young,
Bloodno. Supplement 1 (2023): 1340-1340
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