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Estrogen is a critical factor in many diseases and cancers. Altering its activity through its multiple receptors is critical to the treatment of cancers and other diseases. We are developing new approaches to diagnose and treat breast, endometrial and ovarian cancers based on the discovery of a new estrogen receptor named GPR30/GPER. Our discovery of GPER-selective agonists and antagonists provide the opportunity to discover the roles of GPER in normal physiology and pathophysiology, including in metabolism (obesity and diabetes), cardiovascular function (atherosclerosis, hypertension), immune system (inflammation) and cancer.
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论文共 352 篇作者统计合作学者相似作者
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Xing Zhang,Xiaofeng Ding,Chunqing Wang,Que Le,Dandan Wu,Anying Song, Guixiang Huang,Liping Luo,Yan Luo,Xin Yang,Aleyah E. Goins, Sharina P. Desai,
Eric A. Ariazi,Eugen Brailoiu,Smitha Yerrum, Heather A. Shupp,Michael J. Slifker,Heather E. Cunliffe,Michael A. Black, Anne L. Donato, Jeffrey B. Arterburn,Tudor I. Oprea,Eric R. Prossnitz, Nae J. Dun,
crossref(2023)
BRITISH JOURNAL OF PHARMACOLOGY (2023): S23-S144
Annual review of pharmacology and toxicology (2023): 295-320
Eric A. Ariazi,Eugen Brailoiu,Smitha Yerrum, Heather A. Shupp,Michael J. Slifker,Heather E. Cunliffe,Michael A. Black, Anne L. Donato, Jeffrey B. Arterburn,Tudor I. Oprea,Eric R. Prossnitz, Nae J. Dun,
crossref(2023)
IUPHAR/BPS guide to pharmacology CITEno. 1 (2023)
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Eric A. Ariazi,Eugen Brailoiu,Smitha Yerrum, Heather A. Shupp,Michael J. Slifker,Heather E. Cunliffe,Michael A. Black, Anne L. Donato, Jeffrey B. Arterburn,Tudor I. Oprea,Eric R. Prossnitz, Nae J. Dun,
crossref(2023)
Richard A Pepermans,Eric R Prossnitz
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