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职业迁徙
个人简介
Dr Water’s (nee Al Nadaf) PhD was completed in comparative genomics and epigenetics from the Australian National University in 2012 under the supervision of one of Australia’s most successful and high-profile scientist, Professor Jenny Graves (the 2017 Prime Minister’s Prize for Science winner). Dr Waters recently established (and runs) the molecular integrative Cystic Fibrosis (miCF) Research Lab at UNSW Sydney, Australia. The lab is the molecular node of the miCF Research Centre (Sydney Children’s Hospital), which was established as a collaborative effort between researchers, and clinicians. Dr Waters’ research aims to understand epithelial developmental and the role aberrant epigenetic processes play in progression and pathophysiology of disease. She has created the first Australian biobank (miCF AVATAR biobank) of stem cell derived airway and gut organoids. To date, her team have created primary stem cell models from over 200 CF patients from 11 CF clinics around Australia and Healthy donors. She has created a multi-analyte platform of in silico molecular dynamics simulations, in vitro CFTR functional assays and an array of ‘omics technologies’. Her group are applying this platform to provide personalized molecular phenotyping, drug screening, cell therapy and host-pathogen interactions for CF patients. In 2020, the latter (co-culture airway organoid with pathogens) was pivoted to COVID-19 to delineate the innate immune response to SARS-CoV2 infection.
研究兴趣
论文共 73 篇作者统计合作学者相似作者
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Kim L. McIntyre,Shafagh A. Waters, Ling Zhong,Gene Hart-Smith,Mark Raftery, Zahra A. Chew, Hardip R. Patel, Jennifer A. Marshall Graves,Paul D. Waters
Genome Biologyno. 1 (2024): 1-19
Jessie J.-Y. Chang, Samantha Grimley,Bang M. Tran, Georgia Deliyannis, Carolin Tumpach, An N.T. Nguyen, Eike Steinig, JianShu Zhang, Jan Schröder,Leon Caly, Julie McAuley,Sharon L. Wong,
iScienceno. 6 (2024): 110009
Cell & bioscienceno. 1 (2023): 132-19
Journal of Cystic Fibrosis (2023): S28-S28
Journal of personalized medicineno. 5 (2023): 864-864
NATURE COMMUNICATIONSno. 1 (2023): 6604-13
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 16 (2023)
Journal of Cystic Fibrosis (2023): S17-S18
International Journal of Molecular Sciencesno. 6475 (2023): 6475
Nicholas C Lister, Ashley M Milton,Hardip R Patel,Shafagh Waters,Benjamin J Hanrahan, Kim L McIntyre,Alexandra M Livernois, Lee Kian Wee, Alessa R Ringel,Stefan Mundlos,Michael I Robson,Linda Shearwin-Whyatt,
biorxiv(2023)
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