基本信息
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职业迁徙
个人简介
M.Sc.: The Technical University of Norway, Trondheim, Norway, 1973. Ph.D.: The University of Oslo, 1979. Dissertation: Interaction of the toxic lectins abrin, ricin and modeccin with mammalian cells.
1979- cont. Senior biochemist at The Institute for Cancer Research at the Norwegian Radium Hospital, Oslo, Norway. 1996- Professor of Biochemistry at the University of Oslo (in addition to the position at the Norwegian Radium Hospital).
Visiting scientist: The University of Michigan, Ann Arbor, USA, 3 months, 1979. The Biological Laboratories, Harvard, Cambridge, USA, 2 months, 1980.
Awards and Honours:
1989: Anders Jahres Medical Prize for Younger Scientists.
1990: Award of The Norwegian Research Council for Science and the Humanities.
1993: Member of The Norwegian Academy of Science.
1995: Stiansen's Biomedical Prize.
1998: King Olav V´s Cancer Research Prize.
1998: Elected member of EMBO.
1999: Award from the Res.Comp. of the the Norwegian Radium Hospital.
2002: Elected member of Academia Europaea.
2007: Member of the centre of excellence: Centre for Cancer Biomedicine.
2007: Honorary Doctor at the University of Copenhagen, Denmark.
2010: Member of the American Academy of Microbiology.
2014: The Fridtjof Nansen prize for excellent research in science and medicine.
Publications and Research Interests:
Number of articles:~280. The publications include studies in the following fields: Mechanism of action of toxins, virology, anion transport and regulation of intracellular pH, endocytosis and intracellular transport. 2 patents on related subjects.
Publications
Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
PLoS One, 10 (5), e0129214
PubMed 26017782
Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T (2015)
Novel Furin Inhibitors with Potent Anti-infectious Activity
ChemMedChem, 10 (7), 1218-31
PubMed 25974265
Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
Biochem J, 470 (1), 23-37
PubMed 26251444
Skotland T, Iversen TG, Torgersen ML, Sandvig K (2015)
Cell-Penetrating Peptides: Possibilities and Challenges for Drug Delivery in Vitro and in Vivo
Molecules, 20 (7), 13313-23
PubMed 26205056
Slominska-Wojewódzka M, Sandvig K (2015)
The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation
Molecules, 20 (6), 9816-46
PubMed 26023941
Sokolowska I, Pilka ES, Sandvig K, Wegrzyn G, Slominska-Wojewódzka M (2015)
Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells
BMC Cell Biol, 16, 1
PubMed 25655076
Øverbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A (2015)
Identification of prostate cancer biomarkers in urinary exosomes
Oncotarget (in press)
PubMed 26196085
Publications 2014
Asp N, Pust S, Sandvig K (2014)
Flotillin depletion affects ErbB protein levels in different human breast cancer cells
Biochim Biophys Acta, 1843 (9), 1987-96
PubMed 24747692
研究兴趣
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