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个人简介
The focus of Dr. Kim’s laboratory research is to identify the regulatory mechanism of inflammatory function of dendritic cells under both homeostatic and inflammatory conditions. To understand the molecular mechanisms underlying inhibition of development of autoimmune diseases, particularly in systemic lupus and inflammatory bowel diseases, we are using an animal model of SLE which has a dendritic specific deletion of transcription factor, Blimp-1.
Dr. Kim recently expanded her research to the area of PRDM1 (human gene encoding Blimp-1) susceptibility loci to lupus and alteration of metabolism in follicular helper T cells and autoreactive B cells, which will further enhance the understanding of the mechanism in human diseases. Specific focuses are:
Function of Blimp-1 in the regulation of dendritic cell homeostasis
Autoreactive repertoire in helper T cells in SLE
Sex hormone-mediated regulation of dendritic cell function
Metabolism in follicular helper T cells and age-associated B cells in SLE
Dr. Kim recently expanded her research to the area of PRDM1 (human gene encoding Blimp-1) susceptibility loci to lupus and alteration of metabolism in follicular helper T cells and autoreactive B cells, which will further enhance the understanding of the mechanism in human diseases. Specific focuses are:
Function of Blimp-1 in the regulation of dendritic cell homeostasis
Autoreactive repertoire in helper T cells in SLE
Sex hormone-mediated regulation of dendritic cell function
Metabolism in follicular helper T cells and age-associated B cells in SLE
研究兴趣
论文共 47 篇作者统计合作学者相似作者
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Frontiers in immunology (2024): 1362858-1362858
Frontiers in Immunology (2024)
FRONTIERS IN IMMUNOLOGY (2024)
HEPATOLOGY (2023): S2139-S2141
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Ivan Ramirez De Oleo, Vera Kim,Yemil Atisha-Fregoso,Andrew J Shih,Kyungwoo Lee,Betty Diamond,Sun Jung Kim
Frontiers in immunology (2023): 1241531
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 48 (2023)
JOURNAL OF IMMUNOLOGYno. 1 (2022)
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JCI INSIGHTno. 11 (2022)
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