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The role and regulation of intestinal epithelial stem cells in health and disease. These progenitors compose one of the largest populations of epithelial stem cells in the human body and are the source of rapid and continuous renewal of the absorptive epithelial lining of the intestine. We currently use mouse models to define their molecular properties and determine how they interact with the surrounding mesenchymal stem cell niche.
The role and regulation of intestinal epithelial stem cells in health and disease. These progenitors compose one of the largest populations of epithelial stem cells in the human body and are the source of rapid and continuous renewal of the absorptive epithelial lining of the intestine. We currently use mouse models to define their molecular properties and determine how they interact with the surrounding mesenchymal stem cell niche.
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biorxiv(2024)
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Tesfaye Yadete, Kingsley Njoku,Joao Bettencourt-Silva, Matthew Liu,Vibha Anand,Uri Kartoun,Natasha Mulligan,Eileen Koski,Thaddeus S. Stappenbeck,Julia J. Liu
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