Pyicos: a flexible tool library for analyzing protein-nucleotide interactions with mapped reads from deep sequencing

JBI'10 Proceedings of the 10th Spanish conference on Bioinformatics for Personalized Medicine(2010)

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摘要
Deep DNA or RNA sequencing and posterior mapping to a reference sequence is becoming a standard procedure in molecular biology research. Analyzing millions of mapped reads is a challenging task that doesn't have a unique solution, because experiments using deep sequencing technology vary a great deal among each other. This is why we have developed a flexible tool library called Pyicos, which aims to help biologists in their research when performing their analysis on mapped reads.
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关键词
great deal,flexible tool library,molecular biology research,challenging task,rna sequencing,deep sequencing technology,posterior mapping,deep dna,reference sequence,analyzing million,protein-nucleotide interaction
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