Lactic acidosis after cardiac surgery is associated with polymorphisms in tumor necrosis factor and interleukin 10 genes.

Thomas Ryan,Joanna Balding,Eilis M McGovern,John Hinchion,Wendy Livingstone,Zeb Chughtai,Owen P Smith

The Annals of Thoracic Surgery（2002）

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摘要

Background. Lactic acidosis after cardiac surgery is a manifestation of excess cytokine production. Cytokine-related genetic polymorphisms account for variability in cytokine response and may predispose to the development of lactic acidosis after cardiac surgery.

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关键词

polymerase chain reaction,polymorphism,tumor necrosis factor

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