Frailty Index as a Major Indicator of Aging Processes and Mortality in Elderly: Results From Analyses of the National Long Term Care Survey Data
msra(2017)
摘要
To better understand mortality change with age capturing the variability in
individuals' rates of aging, we performed comprehensive analysis of statistical
properties of a cumulative index of age-associated disorders (deficits), called
a "frailty index" (FI). This index is calculated as the proportion of the
health deficits in an individual. It is found, first, that frequency,
time-to-death, mortality-rate, and relative-risk-of-death exhibit remarkably
similar FI- and age- patterns. Second, the FI, on the one hand, and mortality
rate and relative risk, on the other hand, also exhibit similar age patterns
with accelerated increase up to oldest-old ages and with subsequent
deceleration and even decline. Third, distribution of the FI with time-to-death
is sharper than that of age with time-to-death. These and related findings
support the conclusion that the FI can describe aging processes and population
heterogeneity. We also discuss the ability of the FI to capture physiological
processes underlying aging both on individual and population levels.
更多查看译文
关键词
cumulant,mortality rate,indexation,relative risk
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要