A Synthetic Protein Selected for Ligand Binding Affinity Mediates ATP Hydrolysis
Acs Chemical Biology, Volume 4, Issue 8, 2009, Pages 649-658.
How primitive enzymes emerged from a primordial pool remains a fundamental uranswered question with Important practical implications in synthetic biology. Here we show that a de novo evolved ATP binding protein, selected solely on the basis of its ability to bind ATP, mediates the regiospecific hydrolysis of ATP to ADP when crystallized w...More
Full Text (Upload PDF)
PPT (Upload PPT)