Evolution of hepatitis B virus polymerase mutations in a patient with HBeAg-positive chronic hepatitis B virus treated with sequential monotherapy and add-on nucleoside/nucleotide analogues.
Clinical Therapeutics（2009）
摘要
Background: Nucleoside/nucleotide analogues are a fundamental tool for the treatment of chronic hepatitis B virus (HBV). Sequential anti-HBV treatment might lead to the selection of mutations.
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关键词
hepatitis B virus,nucleoside/nucleotide analogues,drug resistance,mutations
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