Synthesis and study of 9-deazaguanosine derivatives as potential inhibitors of RNA virus replication.

Marie Hamann,Claire Pierra,Richard Storer, Jean-Pierre Sommadossi,Anna Giulia Loi,Alessandra Cadeddu,Maura Fanti,Nadia Boscu,Fabiola Bassetti,Michel Liuzzi, Gilles Gosselin

Nucleic acids symposium series（2008）

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摘要

9-Deazaguanosine and the alpha and beta anomers of its 2'-C-methyl counter part, have been synthesized and evaluated against a broad range of RNA viruses, including hepatitis C virus.

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