Preparation and Blood Compatibility of Oxidized-chitosan Films

Chitosan membrane was modified by the selective oxidization of chitosan molecules on its surface with NO2 gas. FTIR spectra indicated there were plenty of –COOH and –COO- groups on the modified membrane surface. The SEM study showed the modified membrane surface was rough rather than smooth as chitosan membrane. All antithrombosis test, hemolysis test and blood cell morphology observation with SEM revealed that modified chitosan membranes have superior blood compatibility to chitosan.