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Differential Immediate Early Gene Expression In Conditional Hepatitis B Virus Px-Transforming Versus Nontransforming Hepatocyte Cell Lines

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 4 (1999): 2327-2336

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We report construction and characterization of tetracycline-controlled hepatitis B virus pX-expressing hepatocyte (AML12) cell lines. These cell lines were constructed in AML12 clonal isolates (clones 3 and 4), which express constitutively the tetracycline-controlled transactivator. Since pX is implicated in HCC, this immortalized hepatoc...更多

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