The discovery of thienopyridine analogues as potent IκB kinase β inhibitors. Part II
Jiang-Ping Wu,Roman Fleck,Janice Brickwood,Alison Capolino,Katrina Catron,Zhidong Chen,Charles Cywin,Jonathan Emeigh,Melissa Foerst,John Ginn,Matt Hrapchak,Eugene Hickey,Ming-Hong Hao,Mohammed Kashem,Jun Li,Weimin Liu,Tina Morwick,Richard Nelson,Daniel Marshall,Leslie Martin,Peter Nemoto,Ian Potocki,Michel Liuzzi,Gregory W. Peet,Erika Scouten,David Stefany,Michael Turner,Steve Weldon,Clare Zimmitti,Denise Spero,Terence A. Kelly Bioorganic & Medicinal Chemistry Letters(2009)
摘要
An SAR study that identified a series of thienopyridine-based potent IκB Kinase β (IKKβ inhibitors is described.
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关键词
Thienopyridine,IkB Kinase b,IKKb,Inhibitors
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