Improvement of Bloodcompatibility of a Poly-4-methyl-1-pentene Gas Exchange Membrane by Endothelialization

B Wiegmann,C Hess,A Hilfiker,A Haverich,S Fischer

The thoracic and cardiovascular surgeon（2010）

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摘要

Objectives: The use of artificial medical devices with blood contacting surfaces is inter alia limited by activation of the coagulation system. Aiming towards the engineering of a bioartificial lung, the improvement of the bloodcompatibility by a seeded endothelial monolayer onto a heparin/albumin coated gas exchange membrane (PMP) was investigated.

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