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Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase.

MOLECULAR AND CELLULAR BIOLOGY, no. 2 (1999): 1547-1557

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Proteins to be transported into the nucleus are recognized by members of the importin-karyopherin nuclear transport receptor family. After docking at the nuclear pore complex (NPC), the cargo-receptor complex moves through the aqueous pore channel. Once cargo is released, the importin then moves back through the channel for new rounds of ...更多

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