763: Long Term Maternal Outcome of HELLP Syndrome

ObjectiveTo evaluate subsequent pregnancy outcome and long-term prognosis after HELLP syndrome.Study Design128 patients with a history of HELLP syndrome were followed from 1-31 years (average 5). These patients were asked to fill out questionnaires and send their medical records. Outcome variables included maternal demographics, results of index pregnancy, outcomes of subsequent pregnancies and long-term maternal morbidity. Data are presented as mean standard deviation or as n(%).ResultsAmong 128 patients, 82% were Caucasian with a mean age 30.5±4.4 years(range 18-41) at index pregnancy. 81% had cesarean at mean gestational age (GA) 32.6±5.1 weeks. 34% had blood products transfusion,38% were admitted to ICU,2% had liver failure and 3% required dialysis at index pregnancy. On follow up 50 women had subsequent pregnancies: table below summarizes outcome in subsequent pregnancy and maternal long term outcome. Birth control pills (27%) was the most common method of contraception followed by vasectomy(14%). During follow up, 5% of infants had attention deficit disorder and 8% had developmental delay.ConclusionPatients with a history of HELLP syndrome are at increased risk for recurrent preeclampsia and HELLP syndrome as well as increased long-term morbidities particularly depression and chronic hypertension. This data is important for patient counseling. ObjectiveTo evaluate subsequent pregnancy outcome and long-term prognosis after HELLP syndrome. To evaluate subsequent pregnancy outcome and long-term prognosis after HELLP syndrome. Study Design128 patients with a history of HELLP syndrome were followed from 1-31 years (average 5). These patients were asked to fill out questionnaires and send their medical records. Outcome variables included maternal demographics, results of index pregnancy, outcomes of subsequent pregnancies and long-term maternal morbidity. Data are presented as mean standard deviation or as n(%). 128 patients with a history of HELLP syndrome were followed from 1-31 years (average 5). These patients were asked to fill out questionnaires and send their medical records. Outcome variables included maternal demographics, results of index pregnancy, outcomes of subsequent pregnancies and long-term maternal morbidity. Data are presented as mean standard deviation or as n(%). ResultsAmong 128 patients, 82% were Caucasian with a mean age 30.5±4.4 years(range 18-41) at index pregnancy. 81% had cesarean at mean gestational age (GA) 32.6±5.1 weeks. 34% had blood products transfusion,38% were admitted to ICU,2% had liver failure and 3% required dialysis at index pregnancy. On follow up 50 women had subsequent pregnancies: table below summarizes outcome in subsequent pregnancy and maternal long term outcome. Birth control pills (27%) was the most common method of contraception followed by vasectomy(14%). During follow up, 5% of infants had attention deficit disorder and 8% had developmental delay. Among 128 patients, 82% were Caucasian with a mean age 30.5±4.4 years(range 18-41) at index pregnancy. 81% had cesarean at mean gestational age (GA) 32.6±5.1 weeks. 34% had blood products transfusion,38% were admitted to ICU,2% had liver failure and 3% required dialysis at index pregnancy. On follow up 50 women had subsequent pregnancies: table below summarizes outcome in subsequent pregnancy and maternal long term outcome. Birth control pills (27%) was the most common method of contraception followed by vasectomy(14%). During follow up, 5% of infants had attention deficit disorder and 8% had developmental delay. ConclusionPatients with a history of HELLP syndrome are at increased risk for recurrent preeclampsia and HELLP syndrome as well as increased long-term morbidities particularly depression and chronic hypertension. This data is important for patient counseling. Patients with a history of HELLP syndrome are at increased risk for recurrent preeclampsia and HELLP syndrome as well as increased long-term morbidities particularly depression and chronic hypertension. This data is important for patient counseling.