T (brachyury) gene duplication confers major susceptibility to familial chordoma

Xiaohong R Yang,David Ng,David A Alcorta,Norbert J Liebsch,Eamonn Sheridan,Sufeng Li,Alisa M Goldstein,Dilys M Parry,Michael J Kelley

NATURE GENETICS（2009）

引用 265|浏览15

暂无评分

摘要

Dilys Parry and colleagues show that duplications of the T gene confer susceptibility to familial chordoma, a cancer of presumed notochordal origin. The T gene product, known as brachyury, is a transcription factor that plays an important role in notochord development.

查看译文

关键词

comparative genomic hybridization,gene duplication,genome wide association study

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要