Potent, low molecular weight thrombin receptor antagonists.

S Chackalamannil,D Doller,K Eagen,M Czarniecki,H S Ahn,C J Foster,G Boykow

Bioorganic & Medicinal Chemistry Letters（2001）

引用 32|浏览13

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摘要

Several benzimidazole derivatives have been identified as potent thrombin receptor (PAR-1) antagonists as represented by compound 1h, which showed an IC50 of 33 nM.

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关键词

thrombin,receptor,molecular

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