An Architecture for Collaborative Translational Research Utilizing the Honest Broker System

Translational biomedical research involves a diverse group of researchers, data sources and data types voluminous quantities. A collaborative research application is needed to connect these diverse elements. Two approaches are used to integrate biomedical research data; a central data warehouse approach in what all the information is imported into it and a mediator approach which integrates the data on demand. We propose the Beaumont BioBank Integration Management System (BIMS), a collaborative research architecture based on the mediator approach utilizing the Honest Broker System. Our system provides collaborative, flexible and secure environment capable of accelerating biomedical research.