Effects of Broccoli (Brassica oleracea, italica group) Sprouts Grown under Various Lighting Conditions on IL-7 and TGF-.BETA. Secretion by Intestinal Epithelium

The effects of lighting conditions during the growing period of broccoli (Brassica oleracea, italica group) sprouts on their activity to modulate IL-7 and TGF-beta production by intestinal epithelium were investigated. Broccoli sprouts were grown under various LEDs (16/8h light/ dark period) for 3 days after they were grown under a fluorescent light with a16/8h light/dark photoperiod for 3 days. We examined the effects of the extracts from leaves and stalks of the secretion of IL-7 and TGF-beta from Caco-2 cells, which are used as in vitro models of intestinal epithelium. The results suggested that aspects of lighting conditions, such as the wavelength of light and the photoperiodic cycle, affect the activity to modulate IL-7 and TGF-beta secretion by the intestinal epithelium.