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Bioactive and model peptides characterized by the helicogenic (αMe)Phe residue

TETRAHEDRON, no. 17 (1993): 3641-3653

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Abstract

We have synthesized and fully characterized the hypersweet super-aspartame analogue pCN-C6H4-NHCO-L-Asp-L-(alphaMe)Phe-OMe 1; the [D-(alphaMe)Phe]3-analogue of the formyl-methionyl tripeptide chemoattractant HCO-L-Met-L-Leu-D-(alphaMe)Phe-OMe 2, the first D-chemotactic peptide being found more active than its L-diastereomer; and the model...More

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